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7.6 Bipolar disorder

Hello everyone! Welcome to advanced neurobiology! Neuroscience is a wonderful branch of science on how our brain perceives the external world, how our brain thinks, how our brain responds to the outside of the world, and how during disease or aging the neuronal connections deteriorate. We’re trying to understand the molecular, cellular nature and the circuitry arrangement of how nervous system works. Through this course, you'll have a comprehensive understanding of basic neuroanatomy, electral signal transduction, movement and several diseases in the nervous system. This advanced neurobiology course is composed of 2 parts (Advanced neurobiology I and Advanced neurobiology Il). They are related to each other on the content but not on scoring or certification, so you can choose either or both. It’s recommended that you take them sequentially and it’s great if you’ve already acquired a basic understanding of biology. Thank you for joining us!

Taught By

Chenjian Li
Professor
Donggen Luo
Research Fellow
Yan Zhang
Professor

Transcript

And then we have bipolar type I disorder.

Bipolar sometimes can cause manic depressions.

So people switch from depression and the manic state.

So during one year sometimes for

several months people can be in a very depressed mood.

And for the other several months he or

she can be in a very manic and excited mood.

So typically involve episode of major depression and mania.

So for both men and women, the instance of this disease is 1%, it's pretty high.

So typical age of onset of bipolar is the late teens or early 20's.

Symptoms of manic episode of bipolar, so

the manic stage or manic episode,

is a irritable mood for at least one week.

And plus three additional symptoms.

And so, what is the symptoms?

So, symptoms for maniac episode is inflated

self-esteem and decreased need for sleep and

unusual talkativeness and pressured speech.

And flight of ideas, racing thoughts.

So, distracted.

Very easy to be distracted, increased activity in daily life.

Excessive involvement in pleasurable activities

with potential for painful consequence.

So these are the symptom for the manic states.

In the course of this bipolar type I is in a cycle,

as we said, and if from people to people

the duration of this cycle can vary a lot.

[INAUDIBLE] And one sort of the people in the video

goes through only one cycle in five years.

And 1% of the people goes one cycle every three months.

So.

And also, there is a so called rapid cycle.

It's four or more cycle per year, happen in the patient.

And bipolar, there's some other type of bipolar disorder.

There's bipolar type II.

Bipolar type II refers to the alteration or the change between hypomanic

states to the major depression states.

And there's a cyclothymic disorder.

So this disorder referred to an alteration between depression and hypomanic episode.

And this hypomanic episode.

You can think this is a less where manic state, is elevated expansive and

irritable mood for at least four days.

Symptoms very similar to manic state,

except no marked impairment happened.

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