Toxoplasmosis is say it's caused by Toxoplasma gondii, and the old world I think, we have around eight to 40% cases, but here in Tanzania. There are some few studies, I know, that have been done in, in Tanga region. They got around 30% of patients having cysts of toxoplasmosis, and you, the majority of them, of the people who get toxoplasmosis. They actually live in animals cats, cats are very, very very known to be the reservoir of this disease, toxoplasma. Of course other animals as well, contacting animals becomes very important cause of toxoplasma. And he, the patient's who say, with toxoplasmosis, without really showing any symptoms or signs. But he, what I will say, in the past, in past 10 years of so. Okay? Maybe in the time of HIV/AIDS era, which has caused some immune suppression to people. And this is one of the opportunistic infect, infection which comes in, you see? And the, of course, we know that we have also some people who take chemotherapy. We also have some people who are diabetes,in this area people also can, can get as an, as an opportunistic infection because of suppression of immunity. We have seen cases with HIV AIDS, who comes with neurological deficits. Okay? So the first thing we thing of when that have neurological deficit is toxoplasmosis. Some of them can come with blindness, because of toxoplasmosis. And the, yeah, the, yeah, based on this patient coming with HIV-AIDS majority of them have CD4 count less than hundred, less than hundred. Some, one time I saw a patient with CD4 count of 4. This patient had confusion, and immediately we thought toxoplasmosis. So, we have admitted this year, I think I have seen two cases which we have confirmed, straight confirmed to be toxoplasmosis and this one was confir, these ones were confirmed by, by CT scan of their brain we saw some lesions or toxoplasmosis, but also they had some some of the tests which were done, elisa tests and PCR and they show the toxoplasmosis. While the treatment is also not so easy, the treatment is not also so easy because this is now a double problem, toxoplasmosis and HIV. They could have other opportunistic infections as well like CMV and all these, but I think the treatment, the mainstay of the treatment has remained to be pyrimethamine plus sulfadoxine and that is it. But the problem that's here, is that we don't have the drug for that. Sometimes we have to ask, or we have to buy the, the patient have to buy these drugs from from, from Nairobi, the patients are, that is expensive. And because it is a stage four HIV/AIDS disease, this patient does progress very well, but it is a big problem during the HIV era, toxoplasmosis. And, Prevention is also one of the issues you have move maybe, if they take their ARVs earlier, maybe they won't get that. But also, if they, here it's not easy to say that they should use they shouldn't go away from animals. It's not very easy, but we advise them towards personal hygiene, okay, cooking foods well. And I think that's what we are trying to do, but the point is that toxoplasmosis is high in the list in patients who are, at, who have advanced immunosuppression because of HIV/AIDS, and the treatment is also very difficult because of disease. Yeah.