An overview of the tools, techniques, and practices that can be enacted by policy makers, countries, and organizations to monitor, manage, and react to pandemics and mitigate and govern their impacts. An introductory, multidisciplinary course covering data science, social science, healthcare, and management, paving the way to various courses on specific matters. This course is part of the research project 'Pan-European Response to the Impacts of the COVID-19 and future Pandemics and Epidemics' (PERISCOPE, https://www.periscopeproject.eu/). Funded by the European Commission Research Funding programme Horizon 2020 under the Grant Agreement number 101016233, PERISCOPE investigates the broad socio-economic and behavioural impacts of the COVID-19 pandemic, to make Europe more resilient and prepared for future large-scale risks.