Hello. Welcome to another module, which has two exciting lessons for you. We are going to deal with the human toxome, which might be a term you have never heard before. And I hope you like it afterwards. And we'll talk about exciting technologies. The omics technologies, which comprise things like genomics, like transcriptomics, and metabolomics, proteomics. And I will say a few words to introduce these just to make you understand what this all is about. The toxicology for the 21st century movement is trying to overhaul how toxicology is being done. And first of all, this is depending on technologies because the science of the 21st century is most suited to solve the problem of the 21st century. And one aspect of tile technology which is helping us is the omics technologies. They differ from what we traditionally do in the lab counting dead animals, measuring a very well-specified endpoint to try to get as much information as possible from whatever we are doing. For example, measuring in transcriptomics all of the 27,000 genes of a human being, whether they are changed or not changed. And these technologies form a pillar for toxicology in the 21st century. The Human Toxome Project is a project which I initiated when I came to the US in 2009. And we're just trying to make exactly this combined different omics technologies to derive the underlying mechanisms. The pathways of toxicity In order to help understanding and measure toxic effects on the basis of an understanding of the mechanisms which are used to bring this hazard about. So I hope you enjoyed this, it is really making us dig deeper into new technologies and mechanistic understanding of toxicology.