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Learner Reviews & Feedback for Introduction to Systems Biology by Icahn School of Medicine at Mount Sinai

438 ratings
94 reviews

About the Course

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....

Top reviews

Feb 6, 2016

Very useful course in order to learn the basics in systems biology. You only need some training in biology to understand the concepts but the course is easy to follow and very complete.

Aug 7, 2019

Great foundational material and insights from Prof. Iyengar that supports the 'disruptive' trends underway at the intersection of Computational Biology and Medicine.

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76 - 92 of 92 Reviews for Introduction to Systems Biology

By Karl D

Jul 26, 2017

Good overview of systems biology, but the graded tests are somewhat difficult to understand for someone without a biology background such as myself.

By Connie N

Oct 1, 2020

Really interesting content, but could use a rework on formatting, style, and clarity.

By Alan R d F K M

Jan 20, 2020

Could give more basic information about systems theory

By Milena J

Feb 12, 2016

The lectures were somehow chaotic.

By Mainak B

Feb 23, 2020

Tough and brain storming

By Soheyl M

Nov 27, 2020

The explanations in the course are extremely superficial and do not add anything to the PowerPoint presented in each course. In addition, most of the articles presented in the lectures are hardly discussed which makes it difficult to understand for a beginner in this field.

By Circe M

Aug 11, 2017

Course material was not presented in a matter that flowed naturally. Completing the course didn't lend greatly to my overall understanding in the area though I understand certain aspects very well.

By Carolina A

Apr 19, 2020

I found that the lectures didn't guide me enough. I download the articles and read extra material. I will look for another course to learn more of this part of the specialization.

By Alexandro G A S

Aug 9, 2016

It is a good introductory course, but it relies too much on networks and could be confusing and demoralizing if you intend to pursue a career in systems biology.

By D C

Nov 6, 2019

The course is too specific and advanced. It´s not an introduction.

By Sergey K

Dec 19, 2015

Boring voice. A lot of overcomplicated terms, where you can describe your idea in a much more simple way. In result i feel that lector read this material not to teach people, but just to read it. Disgusting.

By Donna P

Mar 12, 2016

I could not understand instructor. Using subtitles didn't help either as many words came up unintelligible.

By Alexander

Oct 5, 2016

The material is very randomized, and the instructor presents it in an overly complex way.

By Richelle E

Oct 18, 2020

the course/ lecture session doesnt highlight half the stuff that pops up in the exams

By Ahmed N

May 6, 2020

i want to cancel mt subscription in this course

By Ezequiel O G

Jul 2, 2020

muy malo, no lo recomiendo, para nada


Jun 6, 2020

too boring