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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

3,921 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Jul 3, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials


Sep 18, 2019

This course would be most useful to the participant if pursued within a short time-frame, of maximum of 6 weeks. Both lecturers were clear and good communicators. I would take more of their classes.

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626 - 650 of 662 Reviews for Design and Interpretation of Clinical Trials

By Shizhao D

Apr 21, 2018

the quiz questions can be more in-depth

By Kumar S

Feb 10, 2019

its quite good course for overview....

By Megan D

Apr 27, 2020

Very informative, and great overview

By Elisa M S

Jun 5, 2019

The good basis of clinical trials

By Jennifer R R

Jul 16, 2021

Engaging materials and visuals.

By Ilunga M

Jun 28, 2020

I wanted to learn more and more

By Miguel M V

Aug 26, 2020

would have wanted more content

By Angela J

Oct 21, 2016

Good introductory course.

By gabriel c

Nov 9, 2019

it was very good class

By Kamesh G

Oct 23, 2016

Great work! Thank you.

By Ernesto G G

Nov 21, 2021

Very Good, Than You!

By Suha A

Aug 29, 2021

Nice ,clear course

By Sumit S

Dec 20, 2017

Excellent course.

By Rahma m

Dec 26, 2018

Excellent course


Sep 29, 2018

It was amagazin

By Qier W

Sep 19, 2020

Great teacher!

By 24 S N

Aug 22, 2020

Usefull course

By Muhammed E M

Aug 5, 2020

Good course !

By Xiaomin W

Dec 22, 2020

Very good!

By natalia r

Jan 19, 2020

Very good!


Oct 28, 2019



Jun 26, 2022

Od ne

By Adeola A

Jan 5, 2017


By barah k a

Mar 10, 2017


By Soujanya K

Jul 14, 2022