Johns Hopkins University
Design and Interpretation of Clinical Trials
Johns Hopkins University

Design and Interpretation of Clinical Trials

Taught in English

Some content may not be translated

144,131 already enrolled


Gain insight into a topic and learn the fundamentals

Janet Holbrook, PhD, MPH
Lea T. Drye, PhD

Instructors: Janet Holbrook, PhD, MPH


(4,248 reviews)

10 hours to complete
3 weeks at 3 hours a week
Flexible schedule
Learn at your own pace

Details to know

Shareable certificate

Add to your LinkedIn profile


6 quizzes

See how employees at top companies are mastering in-demand skills


Earn a career certificate

Add this credential to your LinkedIn profile, resume, or CV

Share it on social media and in your performance review


There are 6 modules in this course

This week, we explore different types of trial designs, including parallel, crossover, group allocation, factorial, large simple, equivalency, non-inferiority, and adaptive designs.

What's included

5 videos3 readings1 quiz2 discussion prompts

This week we discuss two key design features of randomized clinical trials used to protect against bias, randomization and masking.

What's included

3 videos1 reading1 quiz3 discussion prompts

This week focuses on a key design issue - selecting the primary outcome. We will also cover the gold standard for analysis of clinical trials, which is including all the participants in the analysis regardless of their actual treatment.

What's included

4 videos1 reading1 quiz2 discussion prompts

This week focuses on a key issue in the field of clinical trials, the ethics of experimentation in humans.

What's included

2 videos6 readings1 quiz2 discussion prompts

This week, we focus on reporting results of clinical trials in publications. We cover the Consolidated Standards of Reporting Trials (CONSORT) guidelines.

What's included

3 videos3 readings1 quiz2 discussion prompts

This week, we focus on whether RCTs are still the gold standard for evaluating evidence.

What's included

3 videos2 readings1 quiz2 discussion prompts


Instructor ratings
4.7 (955 ratings)
Janet Holbrook, PhD, MPH
Johns Hopkins University
4 Courses159,070 learners
Lea T. Drye, PhD
Johns Hopkins University
1 Course144,131 learners

Offered by

Recommended if you're interested in Research

Why people choose Coursera for their career

Felipe M.
Learner since 2018
"To be able to take courses at my own pace and rhythm has been an amazing experience. I can learn whenever it fits my schedule and mood."
Jennifer J.
Learner since 2020
"I directly applied the concepts and skills I learned from my courses to an exciting new project at work."
Larry W.
Learner since 2021
"When I need courses on topics that my university doesn't offer, Coursera is one of the best places to go."
Chaitanya A.
"Learning isn't just about being better at your job: it's so much more than that. Coursera allows me to learn without limits."

Learner reviews

Showing 3 of 4248


4,248 reviews

  • 5 stars


  • 4 stars


  • 3 stars


  • 2 stars


  • 1 star



Reviewed on Jun 1, 2018


Reviewed on Jul 3, 2018


Reviewed on Oct 25, 2019

New to Research? Start here.


Open new doors with Coursera Plus

Unlimited access to 7,000+ world-class courses, hands-on projects, and job-ready certificate programs - all included in your subscription

Advance your career with an online degree

Earn a degree from world-class universities - 100% online

Join over 3,400 global companies that choose Coursera for Business

Upskill your employees to excel in the digital economy

Frequently asked questions