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Learner Reviews & Feedback for Introduction to Systems Biology by Icahn School of Medicine at Mount Sinai

422 ratings
90 reviews

About the Course

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....

Top reviews


Feb 07, 2016

Very useful course in order to learn the basics in systems biology. You only need some training in biology to understand the concepts but the course is easy to follow and very complete.


Aug 08, 2019

Great foundational material and insights from Prof. Iyengar that supports the 'disruptive' trends underway at the intersection of Computational Biology and Medicine.

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26 - 50 of 88 Reviews for Introduction to Systems Biology

By Nurzhan A

Jun 16, 2020

A fantastic introductory course. One should really treat this as an overview that needs to be followed by further study.

By Doreen B

Jun 07, 2019

Great introduction and overview. Exams are especially well thought out.

By Zhengyuan X

Jul 24, 2018

Really great course! Can't wait to learn more about systems biology!


Jul 18, 2017

fascinating, difficult, and interesting course. Thanks so much!

By Mac D G

Jan 15, 2018

that corse was really beneficial and useful for me. Thanks a lot

By Adriana A C T

Jul 20, 2020

aulas muito dinâmicas e muito bem explicadas, adorei o curso.


Mar 02, 2016

Very very very interesting!!! First step in a new field.

By Areej F

Jan 26, 2018

This course was very engaging and extremely insightful.

By Oluwafeyikemi O

Jul 14, 2020

Wonderful, I really learnt alot

By 刘文昊

Feb 06, 2016

A good step to learn this area.

By Mrinal V

Dec 29, 2015

3rd week and I am loving it! :D

By Aakash S

Feb 23, 2019

Dr. Iyengar was a cool guy.

By Aditya A D

Jun 10, 2020

Good course content!

By changhao l

May 18, 2016

It's very helpful!


Jun 11, 2019


By Danilo A H C

Jul 29, 2020

good course


Jul 30, 2020


By Saad R U

Apr 28, 2019


By farzaneh d d

Jul 29, 2016

very good


Mar 30, 2016


By Mahiban L N

Jun 06, 2020


By Jinwoo J

Aug 19, 2017


By saroj p

Mar 28, 2016



Sep 19, 2020


By Adrián P F

Nov 18, 2018

This sort of course will be kind of useful for sort of improving your knowledge on a sort of concepts related to some kind of areas related to sort of Systems Biology. :) That´s just an innocent joke you will catch if you complete the course. Well, the course could be very useful if you are not especially familiar with Systems Biology, as it was my case. You won't learn how to develop a model from "zero" nor how to use Matlab, but it is a comprehensive compendium of theoretical concepts supported by several well-chosen published examples. It is not easy, but it is not extremely difficult (I completed the entire course in 5 days). Thanks to Dr Ravi Iyengar for the talks and his team for the course. However, the speech should have been more dynamic and fluent sometimes, and with less "sort of" repetitions.