About this Course

18,225 recent views
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Approx. 21 hours to complete
English
Subtitles: English
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Approx. 21 hours to complete
English
Subtitles: English

Offered by

Caltech logo

Caltech

Syllabus - What you will learn from this course

Content RatingThumbs Up99%(2,191 ratings)Info
Week
1

Week 1

1 hour to complete

Welcome

1 hour to complete
3 videos (Total 19 min), 3 readings
3 videos
Description of Parts7m
Introduction: Why Electrons?8m
3 readings
Welcome from Professor Jensen10m
About the Instructor10m
Concept Check Questions: Why Electrons?10m
Week
2

Week 2

3 hours to complete

Currents, Coils, Knobs and Names: Basic anatomy of the electron microscope

3 hours to complete
9 videos (Total 94 min), 8 readings
9 videos
Electron Guns18m
EM Lenses
The Column26m
Sample Chamber14m
Energy Filters7m
Detectors11m
Vacuum Systems9m
Summary and Safety5m
8 readings
Concept Check Questions: Electron Guns10m
Concept Check Questions: Electron Lenses10m
Concept Check Questions: The Column10m
Concept Check Questions: The Sample Chamber10m
Concept Check Questions: Energy Filters10m
Concept Check Questions: Electron Detectors10m
Concept Check Questions: Vacuum Systems10m
Concept Check Questions: Summary and Safety10m
Week
3

Week 3

3 hours to complete

Fourier Transforms and Reciprocal Space for Beginners

3 hours to complete
7 videos (Total 134 min), 6 readings
7 videos
1-D Sine Waves and their Sums32m
1-D Reciprocal Space20m
2-D Waves and Images19m
2-D Transforms and Filters32m
3-D Waves and Transforms13m
Convolution and Cross-Correlation15m
6 readings
Concept Check Questions: 1-D Sine Waves and Their Sums10m
Concept Check Questions: 1-D Reciprocal Space10m
Concept Check Questions: 2-D Waves and Images10m
Concept Check Questions: 2-D Transforms and Filters10m
Concept Check Questions: 3-D Waves and Transforms10m
Concept Check Questions: Convolution and Cross-correlation10m
Week
4

Week 4

4 hours to complete

Image Formation

4 hours to complete
7 videos (Total 164 min), 6 readings
7 videos
Amplitude and Phase Contrast30m
Wave Propagation and Phase Shifts30m
The Contrast Transfer Function33m
Defocus and its Effects21m
Envelopes16m
CTF Correction31m
6 readings
Concept Check Questions: Amplitude and Phase Contrast10m
Concept Check Questions: Wave Propagation and Phase Shifts10m
Concept Check Questions: The Contrast Transfer Function10m
Concept Check Questions: Defocus and its Effects10m
Concept Check Questions: Envelopes10m
Concept Check Questions: CTF Correction10m

Reviews

TOP REVIEWS FROM GETTING STARTED IN CRYO-EM

View all reviews

Frequently Asked Questions

  • Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:

    • The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
    • The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.

More questions? Visit the Learner Help Center.