About this Course

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Beginner Level
Approx. 19 hours to complete
English
Subtitles: English
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Beginner Level
Approx. 19 hours to complete
English
Subtitles: English

Offered by

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Johns Hopkins University

Syllabus - What you will learn from this course

Week
1

Week 1

2 hours to complete

Introduction & Shortcomings of Current Approaches

2 hours to complete
9 videos (Total 66 min), 3 readings, 1 quiz
9 videos
Introduction to the Course14m
Introduction5m
Shortcoming No. 1: Narrative Reviews7m
Shortcoming No. 2: Bias in Reviews7m
Shortcoming No. 3: Evidence Writing4m
Shortcoming No. 4: External Validity10m
Shortcoming No. 5: Assessing New Methods5m
Shortcoming No. 6: Inadequate Reporting7m
3 readings
Letter to Learners10m
Course Learning Objectives10m
Supporting reading10m
1 practice exercise
Practice Quiz 130m
Week
2

Week 2

3 hours to complete

History and Causation

3 hours to complete
11 videos (Total 138 min), 2 readings, 1 quiz
11 videos
Personal First Exposures to Evidence-Based Medicine21m
The Start of EBT16m
The First Conference 2007 to the Start of the EBT Collaboration 201114m
The Evidence-Based Toxicology Collaboration (EBTC)13m
Introduction Causation vs. Correlation18m
The Hill Principles of Epidemiology and their Relation to Toxicology16m
The Problem of Causation in Toxicology16m
Biomarker Concept in Mechanistic Toxicology4m
Mechanistic Validation4m
The Future of Causation in Complex Systems9m
2 readings
Supporting reading10m
Supporting reading10m
1 practice exercise
Practice Quiz 230m
Week
3

Week 3

3 hours to complete

Systematic Review and Meta-Analysis

3 hours to complete
8 videos (Total 101 min), 2 readings, 2 quizzes
8 videos
Systematic Reviews: Definition and Principles26m
Systematic Reviews - Protocol Development15m
Systematic Reviews - Protocol Development (Part 2)19m
History5m
Meta-analysis Guidelines7m
Meta-analysis Protocol, Part 110m
Meta-analysis Protocol, Part 212m
2 readings
Supporting reading10m
Supporting reading10m
2 practice exercises
Practice Quiz 330m
Mid-course exam30m
Week
4

Week 4

2 hours to complete

Risk of Bias & Application to Test Methods Comparison

2 hours to complete
8 videos (Total 94 min), 2 readings, 1 quiz
8 videos
Introduction to Risk of Bias Concept in Critical Appraisal of Studies26m
Examples for Risk of Bias Tools 1: Cochrane Collboration4m
Examples for Risk of Bias Tools 2: SYRCLE's RoB Tool5m
Examples of Risk of Bias Tools 3: National Institute for Environmental Health Sciences (NIEHS) - OHAT12m
Quality Assessment in Evidence-Based Toxicology7m
Evidence-Based Toxicology (EBT) and Evidence-Based Toxicology Collaboration (EBTC)11m
Zebrafish Systematic Review22m
2 readings
Supporting reading10m
Supporting reading10m
1 practice exercise
Practice Quiz 410m

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