Chevron Left
Back to Epigenetic Control of Gene Expression

Learner Reviews & Feedback for Epigenetic Control of Gene Expression by The University of Melbourne

739 ratings

About the Course

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Top reviews


Aug 1, 2021

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.


Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

Filter by:

1 - 25 of 201 Reviews for Epigenetic Control of Gene Expression


May 20, 2020

By Ho Y C

May 10, 2020


Jul 24, 2019

By Apoorva S

Jul 21, 2019


May 23, 2020

By Udit G

Nov 28, 2020

By Ismael V M

Jul 24, 2019

By Gaurav S

Mar 7, 2017

By Saurabh M

Jun 29, 2017

By Rodrigo A M F

Nov 2, 2016

By Hennecke D

Nov 25, 2019

By robert t

Mar 22, 2016

By Dong M

Jul 31, 2017

By Didi-Morgan

Aug 30, 2018

By Christie S

Aug 9, 2019

By Talha I

May 16, 2019

By Camilo G

Dec 1, 2020

By Mostafa E

Aug 28, 2017

By Felipe C D S B

Nov 30, 2020

By Arturo M

Aug 28, 2017

By Dr L S N

May 18, 2020

By Miguel L E

Jul 18, 2016

By Beatric S

Nov 12, 2020

By C. R

Aug 21, 2016

By Emiel d J

May 24, 2020