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Learner Reviews & Feedback for Epigenetic Control of Gene Expression by The University of Melbourne

751 ratings

About the Course

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Top reviews


Aug 1, 2021

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.


Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

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101 - 125 of 205 Reviews for Epigenetic Control of Gene Expression

By Inês D R

Dec 20, 2017

Great course! The contents were extremely interesting and all the lectures were wonderfully taught.

By Peter C

May 25, 2020

Very thorough and comprehensive course. Lots of details, complex subject matter clearly explained.

By Коткова М А

Nov 23, 2020

A well-structured course that provides reasonably deep information. It takes time and commitment.

By Felix M

Oct 18, 2022

Very rigorous and challenging course.

I learned a lot!

Highly recommend!

Thanks Dr Blewitt!

By Priscilla O

May 3, 2016

Love this course. I don't have enough time to devote to it but I still get a lot out of it.

By adel

Apr 6, 2017

it's very interesting and very helpful to provide at least a database of the epigentics

By Niharika B

Mar 27, 2016

very well planned course. It makes the student want to pursue epigenetics for a career

By Susan C M

Jan 5, 2018

Fantastic! Incredibly informative.

I have been so busy- but i am always drawn back!

By Barbara J

Nov 27, 2019

This is one of the most difficult and the most helpful courses I have ever taken.

By Liz

Jul 19, 2019

Fantastic! Genes are a whole other universe of their own. I want to learn more.

By Julia F C

May 17, 2020

Excellent course. Highly recommended It has served me for my professional career

By Ana C d S L

May 29, 2017

I strongly recommend this course, I learned a lot more than I expected to learn.

By Dina H

Aug 27, 2019

i think that is a very good course and it will help me in studing biotechnology

By Gerald L

Jul 5, 2017

The best on-line course I have ever done. Excellent presentation and content.

By Pratik A

Nov 25, 2019

Wonderful Course. Recommended for anyone delving into this fascinating field.

By Yujing

Nov 24, 2020

I am immersed myself in this course, i will continue to learn more about it.

By 정현수

Apr 12, 2017

Great course for learning the basic and intermediate level of epigenetics.

By Alex E

Dec 20, 2016

Excellent course, easy to follow, well taught. Great depth of information.

By Ramon P

Sep 30, 2019

This was an amazing course. So much to learn. Dr. Blewitt is amazing.

By Fatima A

Aug 16, 2019

Amazing course, I learned a great, university level material.


By Siting Z

Mar 4, 2018

It's clear and simple to understand the definition and how it works.

By Maria C A L

Sep 16, 2020

It is super great!!!! I love it, I learned a lot whit the course :)

By Amit K

Aug 1, 2017

Excellent course. Thoughtfully put together, very clear teaching.

By Vishnu N

May 19, 2020

the course is very insightful and very interesting till the end.

By Rabbi h

May 9, 2020

Over all a good course. learn a lot about epigenetics and cancer