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Learner Reviews & Feedback for Genome Assembly Programming Challenge by University of California San Diego

283 ratings
52 reviews

About the Course

In Spring 2011, thousands of people in Germany were hospitalized with a deadly disease that started as food poisoning with bloody diarrhea and often led to kidney failure. It was the beginning of the deadliest outbreak in recent history, caused by a mysterious bacterial strain that we will refer to as E. coli X. Soon, German officials linked the outbreak to a restaurant in Lübeck, where nearly 20% of the patrons had developed bloody diarrhea in a single week. At this point, biologists knew that they were facing a previously unknown pathogen and that traditional methods would not suffice – computational biologists would be needed to assemble and analyze the genome of the newly emerged pathogen. To investigate the evolutionary origin and pathogenic potential of the outbreak strain, researchers started a crowdsourced research program. They released bacterial DNA sequencing data from one of a patient, which elicited a burst of analyses carried out by computational biologists on four continents. They even used GitHub for the project: The 2011 German outbreak represented an early example of epidemiologists collaborating with computational biologists to stop an outbreak. In this Genome Assembly Programming Challenge, you will follow in the footsteps of the bioinformaticians investigating the outbreak by developing a program to assemble the genome of the E. coli X from millions of overlapping substrings of the E.coli X genome....

Top reviews

Oct 20, 2020

Really enjoyable and also challenging specialization. I also enjoyed this capstone too. I gathered my interest in Algorithms and Bioinformatics field.

Aug 4, 2018

I would like to say thank you to all who have created this course and specialization! Good material, excellent lecturers!

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26 - 50 of 52 Reviews for Genome Assembly Programming Challenge

By Priyansh B

Jul 28, 2019

May be the course would have given more hints. But a learned a lot from the projects.

By Pradyumn A

Jul 14, 2017

Really tough and enjoyable Project. Learnt something very special.

By Andres F O G

Jul 28, 2020

very challenging course, but still very good and you learn a lot

By Fahmim M S

Sep 6, 2020

It's a great experience with learning a Genome Assembly.

By Enrique A M

Oct 27, 2020

Mil gracias maestro Alexander, Mil gracias Coursera.

By Edgar H F

Mar 12, 2021

It was great! Really tough, but rewarding.

By Manikant R

Jun 5, 2020

Great course, hard but it is worth.

By Ahmad B E

Jan 17, 2018

This is how algorithms should be.

By Shehab E E

Aug 13, 2020

Very Challenging Course

By Pablo E M M

Jun 3, 2018

Greate course


Nov 26, 2020

good course

By Dil M

Sep 6, 2020

good course


Aug 20, 2020


By Muhammad A F B

Dec 11, 2020

Thank YOu


Nov 19, 2020


By SeyedAli A

Aug 11, 2020

hi, this is a hard course and the videos are not sufficient. but finally i finished.

thanks a lot

By Nikhil K

Apr 10, 2020

It is a challenging course, which makes it great.

By Alexander M

Oct 18, 2017

Very complicated tasks; Too much bioinformations

By Prathmesh S J

May 14, 2020

Why we are learn this is biology part

By Chan Y F

Apr 16, 2019

A little bit difficult

By 孙映雪

Apr 11, 2019


By Xi Y

Feb 16, 2017


By Dave

Jul 11, 2020

very good!

By VontMan

Aug 28, 2019

The topic is very interesting but it is very rushed and it is very challenging to pass the test

By Weidong X

Nov 26, 2016