About this Course

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Course 6 of 7 in the
Flexible deadlines
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Beginner Level
Approx. 24 hours to complete
English
Subtitles: French, Portuguese (Brazilian), Russian, English, Spanish
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Course 6 of 7 in the
Flexible deadlines
Reset deadlines in accordance to your schedule.
Beginner Level
Approx. 24 hours to complete
English
Subtitles: French, Portuguese (Brazilian), Russian, English, Spanish

Offered by

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University of California San Diego

Syllabus - What you will learn from this course

Week
1

Week 1

4 hours to complete

Week 1: Introduction to Read Mapping

4 hours to complete
4 videos (Total 33 min), 2 readings, 3 quizzes
4 videos
Why Do We Map Reads? 7m
Using the Trie 10m
From a Trie to a Suffix Tree 11m
2 readings
Course Details10m
Week 1 FAQs (Optional)
1 practice exercise
How Do We Find Disease-Causing Mutations? (Week 1)15m
Week
2

Week 2

4 hours to complete

Week 2: The Burrows-Wheeler Transform

4 hours to complete
3 videos (Total 21 min), 1 reading, 2 quizzes
3 videos
Inverting Burrows-Wheeler 13m
Using Burrows-Wheeler for Pattern Matching 2m
1 reading
Week 2 FAQs (Optional)
Week
3

Week 3

4 hours to complete

Week 3: Speeding Up Burrows-Wheeler Read Mapping

4 hours to complete
4 videos (Total 22 min), 1 reading, 3 quizzes
4 videos
Setting Up Checkpoints 8m
Inexact Matching 6m
Further Applications of Read Mapping 2m
1 reading
Week 3 FAQs (Optional)
1 practice exercise
How Do We Find Disease-Causing Mutations? (Weeks 2-3)20m
Week
4

Week 4

4 hours to complete

Week 4: Introduction to Hidden Markov Models

4 hours to complete
5 videos (Total 42 min)
5 videos
Gambling with Yakuza 12m
From a Crooked Casino to a Hidden Markov Model 9m
The Decoding Problem 5m
The Viterbi Algorithm 7m

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TOP REVIEWS FROM FINDING MUTATIONS IN DNA AND PROTEINS (BIOINFORMATICS VI)

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About the Bioinformatics Specialization

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
Bioinformatics

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