Imperial College London

Immunology: Innate Immune System

This course is part of Immunology: The Immune System and its Failures Specialization

Taught in English

Some content may not be translated

Sophie Rutschmann
Malgorzata (Maggie) Trela

Instructors: Sophie Rutschmann

4,211 already enrolled

Included with Coursera Plus

Course

Gain insight into a topic and learn the fundamentals

4.8

(66 reviews)

Intermediate level

Recommended experience

7 hours (approximately)
Flexible schedule
Learn at your own pace

What you'll learn

  • You will identify key innate immunity cells, molecules, and direct defence mechanisms.

  • You will also learn how our microbiota, the overall micro-organisms found in our body, influences our innate immune response.

  • Finally, you will understand how our innate immune cells inform our adaptive system of the presence of a threat.

Details to know

Shareable certificate

Add to your LinkedIn profile

Assessments

9 quizzes

Course

Gain insight into a topic and learn the fundamentals

4.8

(66 reviews)

Intermediate level

Recommended experience

7 hours (approximately)
Flexible schedule
Learn at your own pace

See how employees at top companies are mastering in-demand skills

Placeholder

Build your subject-matter expertise

This course is part of the Immunology: The Immune System and its Failures Specialization
When you enroll in this course, you'll also be enrolled in this Specialization.
  • Learn new concepts from industry experts
  • Gain a foundational understanding of a subject or tool
  • Develop job-relevant skills with hands-on projects
  • Earn a shareable career certificate
Placeholder
Placeholder

Earn a career certificate

Add this credential to your LinkedIn profile, resume, or CV

Share it on social media and in your performance review

Placeholder

There are 5 modules in this course

In module one, we will explore the main component of the innate immune system. We will start by looking at the surfaces that are first exposed to potential pathogens and how they prevent most pathogens from entering our body. We will then learn about our main innate protective mechanisms and discuss how this inherited system is able to recognise and combat infection. By the end of this module, learners will be able to describe these actors and mechanisms in detail.

What's included

4 videos5 readings2 quizzes

In module two, we will explore a key soluble component of our innate immune system: the complement. We will learn about its main components, how it gets activated by pathogens and how the outcome leads to pathogens destruction. We will also explore how the complement system contributes to other innate immune activities, such as phagocytosis, that is the uptake of microorganisms by immune cell for destruction.

What's included

1 video3 readings1 quiz

In module three, we will investigate how our microbiota plays a protective role in our health. We will first define the human microbiome in more details and explore its influence on various common pathologies such as asthma, diabetes or cancer. The module ends on an opportunity for learners to reflect and share with others on the effects of pro-biotics on our health.

What's included

3 videos2 readings2 quizzes1 discussion prompt

In module four, we will understand how the innate system communicates with the adaptive immune cells. We will explore which cells oversee this essential function and how they capture, digest and present pathogenic molecules to the adaptive immune cells to for their activation. Importantly, we will also investigate how the innate immune response helps this second phase of response to ‘adapt’ to the nature of the infection.

What's included

3 videos1 reading2 quizzes

In module five, we will look at one example of innate cells, called Natural Killers, that are directly able to destroy infected and tumour cells. We will explore how they interact with other immune cells, how they recognise their target cells and the mechanisms they use to lead to their death. Importantly, we will also discover the mechanisms that prevent their mis-activation to prevent the disastrous destruction of health host cells.

What's included

1 video3 readings2 quizzes1 discussion prompt

Instructors

Instructor ratings
4.6 (24 ratings)
Sophie Rutschmann
Imperial College London
5 Courses8,813 learners
Malgorzata (Maggie) Trela
Imperial College London
5 Courses8,813 learners

Offered by

Recommended if you're interested in Basic Science

Why people choose Coursera for their career

Felipe M.
Learner since 2018
"To be able to take courses at my own pace and rhythm has been an amazing experience. I can learn whenever it fits my schedule and mood."
Jennifer J.
Learner since 2020
"I directly applied the concepts and skills I learned from my courses to an exciting new project at work."
Larry W.
Learner since 2021
"When I need courses on topics that my university doesn't offer, Coursera is one of the best places to go."
Chaitanya A.
"Learning isn't just about being better at your job: it's so much more than that. Coursera allows me to learn without limits."

Learner reviews

Showing 3 of 66

4.8

66 reviews

  • 5 stars

    85.07%

  • 4 stars

    10.44%

  • 3 stars

    2.98%

  • 2 stars

    1.49%

  • 1 star

    0%

VH
5

Reviewed on Apr 17, 2023

NM
5

Reviewed on Feb 16, 2024

AA
5

Reviewed on Mar 24, 2023

New to Basic Science? Start here.

Placeholder

Open new doors with Coursera Plus

Unlimited access to 7,000+ world-class courses, hands-on projects, and job-ready certificate programs - all included in your subscription

Advance your career with an online degree

Earn a degree from world-class universities - 100% online

Join over 3,400 global companies that choose Coursera for Business

Upskill your employees to excel in the digital economy

Frequently asked questions