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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

3,556 ratings
608 reviews

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews

Oct 25, 2019

Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic. Thank you.

Sep 18, 2019

This course would be most useful to the participant if pursued within a short time-frame, of maximum of 6 weeks. Both lecturers were clear and good communicators. I would take more of their classes.

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301 - 325 of 603 Reviews for Design and Interpretation of Clinical Trials

By Ernest K

Aug 17, 2016

Great course. I am happy that I could participate.


By Dr G K

Sep 3, 2020

Excellant presentation and crisp sharing of knowledge..

By Vinusha G

Aug 11, 2020

it was very helpful to learn Design and clinical trails


Aug 3, 2020

thank you for these lectures, it was really very useful

By anahita e

Apr 21, 2020

Presented in an engaging and easy to understand format.

By Vikram S

Jan 25, 2021

Very interesting to learn about Clinical trial designs

By Karo L

Oct 30, 2017

Great course! Lots of useful knowledge and real cases.

By Krystyna

Apr 27, 2021

Very refreshing. A great introduction to the subject.

By Michael V C

Aug 18, 2017

Excellent learning resource! Thanks JHU and coursera!

By Leonardo Z

Dec 26, 2016

I learned so much and am excited to take more classes

By Annette A

May 30, 2016

Intresting and informative course for design of clini

By nutthan n

Dec 6, 2020

very useful for people who looking for study design

By Dr. M P P

Jul 2, 2020

Great course, every minute and penny spent is worth

By Malgorzata M

Jan 29, 2017

Great time, I've learned a lot of new informations.

By Alejandro H G

May 24, 2020

Excellent course on the basics of clinical trials!

By Ines L

Jun 27, 2018

very easy to follow and super useful in real life.

By Kanchan B

Feb 10, 2021

great experience learning with coursera thank you

By Ruchika P C

Apr 25, 2020

really like the course, looking forward for more

By Tahir H

Jan 12, 2020

Nice information and happy to enroll this course

By paul s

Aug 16, 2018

they made a complex course simple to understand.

By Ting C L

Jun 26, 2018

Very helpful! Especially for me as an oncologist

By Carina M

Feb 11, 2018

A lot of information about the topic. I like it.

By Neeraj B

Sep 12, 2020

Very good and educational course. Learnt a lot

By Syed M S

Aug 28, 2020

Very informative, Adaptable and Succint course

By Otavio B

Nov 28, 2016

Excellent and very useful course! I recommend!