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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

2,723 ratings
476 reviews

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Jun 05, 2020

I would highly recommend this course as I found it well-structured and helpful. After studying all the materials, I gained a great amount of knowledge in designing and interpretating clinical trail.


Oct 26, 2019

Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic. Thank you.

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426 - 450 of 467 Reviews for Design and Interpretation of Clinical Trials

By Anna I B

Aug 16, 2017

Interesting general overview of clinical trials.

By David A

Oct 19, 2016

Great introductory course to Clinical Trials.

By Luciano R

Sep 04, 2017

Great introductory course on Clinical Trials

By Faisal I

Jun 14, 2020

Well planned and good overview of the topic

By Taher H

Jun 06, 2016

a very good introduction to clinical trail

By Artem K

Aug 02, 2020

In my opinion this course is too short.

By Shizhao D

Apr 22, 2018

the quiz questions can be more in-depth

By Kumar S

Feb 10, 2019

its quite good course for overview....

By Megan D

Apr 27, 2020

Very informative, and great overview

By Elisa M S

Jun 05, 2019

The good basis of clinical trials

By Ilunga M

Jun 28, 2020

I wanted to learn more and more

By miguel m

Aug 26, 2020

would have wanted more content

By Angela J

Oct 21, 2016

Good introductory course.

By abdullah B

Nov 10, 2019

it was very good class

By kamesh g

Oct 23, 2016

Great work! Thank you.

By Sumit S

Dec 20, 2017

Excellent course.

By Rahma m

Dec 26, 2018

Excellent course


Sep 30, 2018

It was amagazin

By Qier W

Sep 19, 2020

Great teacher!

By Shiyona N

Aug 22, 2020

Usefull course

By Muhammed E M

Aug 05, 2020

Good course !

By natalia r

Jan 19, 2020

Very good!


Oct 28, 2019


By Adeola A

Jan 05, 2017


By barah k a

Mar 10, 2017