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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

1,852 ratings
317 reviews

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Jul 04, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials


Oct 26, 2019

Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic. Thank you.

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201 - 225 of 312 Reviews for Design and Interpretation of Clinical Trials

By Aiswarya B

Jun 30, 2017

Very informative!

By Mauricio C

Nov 21, 2016

Very good course.

By Anil R

Jan 11, 2018

Excellent Course

By Gehad M T R

Jul 08, 2017

wonderful course

By Ramesh C

Feb 01, 2017

Excellent Course

By Omar M A A

Jun 26, 2016

Excellent course

By Mahmoud H

Aug 27, 2019

Too long period

By Fernando A V

Mar 01, 2018

Really useful !

By Fernando H D

Oct 04, 2016

Amazing course!

By Christopher H

Dec 30, 2019

Learned a lot!

By Tereza F

Apr 03, 2016

nicely done :)

By Chen W C

Jun 19, 2019

Nice lecture!

By Cansu d M

May 03, 2018

Great course.

By Jyoti B G

Aug 25, 2017

Superb course

By Alma D

Jun 07, 2016

Great course!

By Amer M A S

Mar 07, 2020


By Oluwatobi A

Feb 06, 2020

great course

By Sakis P

Jan 16, 2020

great course

By Tomasz C

Nov 23, 2019

Very helpful

By Jordon J

Mar 01, 2018

Really great

By Uriel A P F

Jan 17, 2018

great course

By Shaker A

Jun 29, 2017

great course

By Andreas K

Jun 03, 2017

great course

By Andrea S

Jan 16, 2017

Great course

By Martha S

Jan 07, 2018