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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

2,738 ratings
476 reviews

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Jun 05, 2020

I would highly recommend this course as I found it well-structured and helpful. After studying all the materials, I gained a great amount of knowledge in designing and interpretating clinical trail.


Oct 26, 2019

Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic. Thank you.

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201 - 225 of 468 Reviews for Design and Interpretation of Clinical Trials

By Tyrnnon S

Jan 15, 2020

Really helpful course to take as an introduction to clinical trial design

By Gaye T

Nov 25, 2019

It was very informative and easy to access, follow and complete course :)

By Ana B C S

Jun 08, 2018

Good way to get closer to Clinical trials and learn the basis about them.

By Diptiman C

Sep 27, 2020

It a great course for some interested in learning about clinical trials.

By jinjie c

Nov 29, 2019

Wonderful Course! I really gained a lot from this course!! Appreciate it

By Bharath K M

Jun 18, 2016

The course really deals with great insights of randomized clinical trial

By sonia y

May 09, 2020

This course is really helpful to know about randomized clinical trials.

By Miguel A

Dec 15, 2019

Excellent free option to engage in better appraisal of clinical trials

By Y M

Jul 04, 2020

Excellent course, i learn so much from this course.

Extensive course.

By Chris M

Jul 19, 2017

Very easy to follow, concise yet informative.

Thank you and well done.

By Dr. V A

Jul 02, 2020

This one really helped me to understand the clinical trial overview.

By Braulio H V S

Nov 19, 2019

Excelente capacitación, contenido y formación.

Recomendado en un 100%

By Maureen V

Feb 12, 2017

An amazing chance to get clear in the clinical trials interpretation

By Alexander M

Oct 16, 2016

Very useful. Important aspects highlighted. Systematic presentation.

By Hebatalla M b

Aug 24, 2019

very interesting course , but need to be shorter and more practical

By Surajit

Jul 08, 2020

Valuable course, Thank you, Johns Hopkins University and Coursera.

By Rajesh S

May 25, 2017

Very good course contains all the materials and excellent material

By Eszter T

May 06, 2020

Excellent course, highly recommended for us, clinical scientists!


Apr 07, 2020

This has given me an in-depth understanding of trials, thank you!

By Sara H

Apr 30, 2020

Very informative and fruitful course with qualified instructors

By Naila M

Aug 24, 2019

Excellent course, I would recommend this to anyone interested.

By Roy Y C

Mar 29, 2016

Easy to read slide materials with concise presentation videos.

By Eric A S

Aug 11, 2020

Very interesting material, clearly and concisely presented.

By Chintan B

Jul 30, 2017

Best course and nicely posted all videos and the material.

By Cliff

Jul 08, 2017

Great course, easy to understand. Good point of referral.