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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

4.7
stars
4,125 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews

SS

Feb 25, 2023

awesome detailedoverviwe of clinical trials. it gave me a new insight. Improved chances of my job selection in the field. I improved on subject a lot during the course. Thank you teachers and coursera

TS

Jul 3, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

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401 - 425 of 691 Reviews for Design and Interpretation of Clinical Trials

By Vanessa P A

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Jan 28, 2020

Amazing content, beautifuly explained.

By Emilio C S J

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Mar 20, 2021

I was very satisfied with the course.

By Peter P

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Feb 7, 2021

Excellent course! Highly recommended!

By Zhi M

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Feb 1, 2021

Very good course, strongly recommend!

By Petre M

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Mar 21, 2019

Useful and interesting course for me.

By Ralph T

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Oct 20, 2017

The course was engaging and on topic.

By Sally M A E

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Oct 10, 2016

amazing and I have understand it tota

By Dr. V K A

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Aug 4, 2022

Course is very useful and excellenat

By Ehsan M

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May 18, 2021

Succinct, practical and informative!

By Dilki T

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Feb 12, 2021

I learned a lot. thank you very much

By Jonathan R

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Dec 31, 2020

Good foundation into Clinical Trials

By Martha R M E

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Sep 1, 2020

I learnt a lot, thank you very much!

By Vasudha R

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Apr 27, 2020

Thank you for the detailed lectures.

By Kocfa C

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Nov 13, 2016

Wonderful course, excellent content!

By Tania C A

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Jun 5, 2022

Me agradó bastante y aprendí mucho.

By Lilia F

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Nov 2, 2020

Very interesting and informational.

By Chukwuma O

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Jun 25, 2020

Extremely useful, really well done!

By Cristina P

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Apr 8, 2020

Very interesting and useful course.

By Mayank P

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Oct 9, 2016

Thanks for such a wonderful course.

By Astghik M

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May 7, 2021

Great course, highly recommend it!

By Thiago C

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Apr 4, 2021

Great course. Really recommend it.

By Michael K

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Oct 12, 2020

Comprehensive & Easy to understand

By Johannes K

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Mar 19, 2020

I can fully recommend this Course!

By Mikhail K

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Aug 2, 2020

An excellent introductory course!

By Jennifer D

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Jun 21, 2018

Very thorough and well-explained!

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