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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

4,123 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Feb 25, 2023

awesome detailedoverviwe of clinical trials. it gave me a new insight. Improved chances of my job selection in the field. I improved on subject a lot during the course. Thank you teachers and coursera


Jul 3, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

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426 - 450 of 691 Reviews for Design and Interpretation of Clinical Trials

By Manshi P

Jun 5, 2020

It was a very informative course

By Tayyab M K

May 8, 2020

awesome course for researchers .

By Rohit S R

Oct 13, 2019

test were hard but time was good

By Chandni B

Mar 13, 2021


By Yuan L

Apr 21, 2020

Comprehensive and informational

By Anaïs F

Mar 23, 2017

Very well, lot of information !

By Manisha D

Aug 30, 2022

awesome! I feel i learnt alot

By Nicole D

Dec 27, 2021

Well written and well taught!

By Eduardo D M R

Oct 29, 2019

Its a great course I loved it

By Etienne D

Sep 21, 2019

An excellent overview o RCT!!

By Paula C L

Feb 8, 2019

Excelente curso muy practico!

By Noor e m

Nov 20, 2016

simple, easy and to the point

By Melody R

Sep 16, 2016

Great course and instructors!

By Laura M

May 19, 2022

Fabulous review, thank you.

By Maliha A

Mar 6, 2022

A perfectly designed course.

By Renata C N

Mar 31, 2021

Great course! Very engaging.

By Alaa m

Apr 1, 2018

excellent very useful course

By Anderson Q

Feb 12, 2021

excellent corse! thank you!

By Lilian C

Nov 27, 2020

A life changing experience.

By Manasvi G

May 4, 2020

Really it is a great course

By Laurence L

Jan 14, 2020

Synthetic and user-friendly

By JoonHo L

Apr 8, 2018

Good. easy, and informative

By cristian r

Nov 17, 2022

muy bueno, excelente curso

By Mhoneesha T

Nov 1, 2021

Good and learner-friendly

By Aya G

Jun 24, 2021

very comprehensive course