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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

4,124 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews


Feb 25, 2023

awesome detailedoverviwe of clinical trials. it gave me a new insight. Improved chances of my job selection in the field. I improved on subject a lot during the course. Thank you teachers and coursera


Jul 3, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

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451 - 475 of 691 Reviews for Design and Interpretation of Clinical Trials


Jan 8, 2021

Cours très complet, merci!

By Santiago G

May 16, 2020

Thorough and comprehensive

By Faisal A R A s

Dec 31, 2020

systematic and organized

By Rafael M - P

Feb 21, 2020

Awesome and clarifying.

By Mostafa R

May 28, 2020

Very informative course

By Zhanwu C

Aug 23, 2018

This is a great course!


Oct 8, 2020

was hard but neccesary

By David B

Feb 25, 2018

Very clearly presented

By Jelle S

Dec 25, 2016

Short but very useful!

By tran n k t

Jun 3, 2021

great course content

By Yu C L

Sep 5, 2019



Oct 21, 2018

el curso es excelente

By Panagiotis K

Nov 29, 2020

Excellent course!!!!

By Dickens O

Jan 16, 2018

I enjoyed the course

By Abdullah M

Sep 2, 2021

very goood

thank you

By Arriola T

Mar 14, 2021

Interesting course;

By Mari M

Jul 20, 2020

Excelente course !!

By Maciej T

Oct 30, 2017

Excellent, engaging

By Geoffrey A

Feb 5, 2021

good course indeed

By Emmanuel O

Aug 4, 2020

Outstanding course

By Twaib S

Jan 16, 2019

i like this course

By Yu-Pu B W

Dec 2, 2016

Very GOOD lesson!!

By Simone E

Nov 29, 2021

Excellent Course!

By Muskaan S

Sep 24, 2021

I learned so much

By Ackrion M

Apr 4, 2021

Excellent Course!