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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

3,590 ratings
612 reviews

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews

Jul 3, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

Jun 4, 2020

I would highly recommend this course as I found it well-structured and helpful. After studying all the materials, I gained a great amount of knowledge in designing and interpretating clinical trail.

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451 - 475 of 607 Reviews for Design and Interpretation of Clinical Trials

By Phob G

Oct 20, 2020

Great course

By Karthikeyan P

Aug 1, 2020

Great Course

By Amer M A S

Mar 7, 2020


By Oluwatobi A

Feb 5, 2020

great course

By Sakis P

Jan 16, 2020

great course

By Tomasz C

Nov 23, 2019

Very helpful

By Jordon J

Mar 1, 2018

Really great

By Uriel A P F

Jan 17, 2018

great course

By Shaker A

Jun 29, 2017

great course

By Andreas K

Jun 3, 2017

great course

By Andrea S

Jan 15, 2017

Great course

By Ehsan M

Sep 3, 2020

best review


Jun 11, 2020

Nice course

By Halimah S B

Apr 27, 2020


By Martha S

Jan 7, 2018


By Just d i

Oct 10, 2016

Very useful

By Basset B

May 4, 2020

good cours

By erica s

Aug 30, 2019

well done.

By Rashad I

Jul 30, 2017



Sep 15, 2021



Apr 28, 2021

very good

By Felipe T G

Feb 21, 2021


By Mario Á

Jan 2, 2021


By asiya p

Dec 1, 2020


By Debanjan D

Apr 22, 2020

Best Ever