We will introduce methods to perform systematic reviews and meta-analysis of clinical trials. We will cover how to formulate an answerable research question, define inclusion and exclusion criteria, search for the evidence, extract data, assess the risk of bias in clinical trials, and perform a meta-analysis.
Introduction to Systematic Review and Meta-Analysis
Johns Hopkins UniversityAbout this Course
244,036 recent views
Learner Career Outcomes
29%
started a new career after completing these courses
23%
got a tangible career benefit from this course
13%
got a pay increase or promotion
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Approx. 13 hours to complete
English
Subtitles: English
Learner Career Outcomes
29%
started a new career after completing these courses
23%
got a tangible career benefit from this course
13%
got a pay increase or promotion
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Approx. 13 hours to complete
English
Subtitles: English
Offered by
Johns Hopkins University
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
Syllabus - What you will learn from this course
1 hour to complete
Introduction
To get the ball rolling, we'll take a broad overview of what to expect in this course and then introduce you to the high-level concepts of systematic review and meta-analysis and take a look at who produces and uses systematic reviews.
1 hour to complete
5 videos (Total 40 min), 3 readings
5 videos
Lecture 1A : Introduction to Systematic Reviews15m
Lecture 1B: Introduction to Meta-Analysis12m
Lecture 1C: Producers and Users of Systematic Reviews8m
Hannah Rothstein, PhD1m
3 readings
Syllabus10m
Pre Course Survey10m
From the Field Videos10m
4 hours to complete
Framing the Question
In this module, we will discuss how to frame a question, as well as scope, elements, and refining the question.
4 hours to complete
7 videos (Total 73 min), 1 reading, 2 quizzes
7 videos
Lecture 2B: Deciding the Type and Scope of Your Question17m
Lecture 2C: Elements of the Question16m
Lecture 2D: Refining the Question10m
Lecture 2E: Some Examples8m
Lecture 2F: Analytic Frameworks10m
Betsy Becker, PhD2m
1 reading
Welcome to the first Peer Assignment!10m
1 practice exercise
Module 210m
2 hours to complete
Searching Principles and Bias Assessment
In this module we will look at finding the evidence, as well as key sources, search strategy, and assessing the risk of bias.
2 hours to complete
11 videos (Total 119 min)
11 videos
Lecture 3A: Finding the Evidence: Searching Principles5m
Lecture 3B: Identifying Key Sources and Techniques for Searching17m
Lecture 3C: Building a High-Quality Search Strategy17m
Lecture 3D: Documenting Your Search and Conclusions8m
Lecture 4A: Why Bias in the Individual Study is Important to a Systematic Review and Meta-Analysis7m
Lecture 4B: Selection Bias18m
Lecture 4C: Information Bias8m
Lecture 4D: Bias in the Analysis15m
Lecture 4E: Displaying Study "Quality" in Your Systematic Review16m
Byron Wallace, Phd2m
2 practice exercises
Module 310m
Module 410m
2 hours to complete
Minimizing Metabias, Qualitative Synthesis, and Interpreting Results
In this module, we will cover minimizing metabias, selection bias, information bias, how to report transparently, qualitative synthesis, and interpreting results.
2 hours to complete
9 videos (Total 88 min)
9 videos
Lecture 5B: Selection Bias22m
Lecture 5C: Information Bias12m
Lecture 5D: Bias in the Analysis15m
Lecture 5E: Reporting Transparently6m
Lecture 6A: Qualitative Synthesis and Interpreting Results Section A7m
Lecture 6B: What is Qualitative Synthesis10m
Lecture 6C: Some Examples5m
Christopher Schmid, PhD1m
2 practice exercises
Module 510m
Module 610m
Reviews
TOP REVIEWS FROM INTRODUCTION TO SYSTEMATIC REVIEW AND META-ANALYSIS
by ATJan 14, 2020
Really excellent information. Would have appreciated more basic discussion of statistical concepts, or a link to resources for those not as familiar with them or without a background in epidemiology.
by AOJan 8, 2018
This is a good introductory course to how and why systematic reviews are performed. I would have liked to have one assignment at the end to try and apply it ourselves but all in all great course !
by MJJan 7, 2019
Although introductory, I do carry out reviews as a researcher. I Learned a lot to improve my systematic reviews through this course. High quality, though the music could be a little less intense.
by PSAug 22, 2019
Introduction to Systematic Review and Meta-Analysis course is a very good source for beginners which provides an overview on fundamental terminology and steps involved in the systematic review.
Frequently Asked Questions
When will I have access to the lectures and assignments?
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
- The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
- The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
What will I get if I purchase the Certificate?
When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
What is the refund policy?
You will be eligible for a full refund until two weeks after your payment date, or (for courses that have just launched) until two weeks after the first session of the course begins, whichever is later. You cannot receive a refund once you’ve earned a Course Certificate, even if you complete the course within the two-week refund period. See our full refund policy.
Is financial aid available?
Yes, Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You’ll be prompted to complete an application and will be notified if you are approved. Learn more.
More questions? Visit the Learner Help Center.
