Course 3 of a four-course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material. This is the third leg of the journey through the defenses your body uses to keep you healthy. We learned about innate immunity and B cell function in the first course. In the second course, we studied T cell function and coordination of the immune response. Fundamentals of Immunology: Inflammation, Tolerance, and Autoimmunity introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues, and organs using metaphors, cartoons, and models to improve understanding and retention. After describing the form, function, origin, and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in an anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawings, and photographs used in the lecture and reproduced in the outline. What You’ll Learn: A survey of immune cells and how they attack pathogens, emphasizing the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity. The inflammatory response and mechanisms of generating tolerance are presented sequentially to emphasize the decision-making in controlling attacks. A survey of autoimmune disease, its characteristics, cause, and treatment. Survey of hypersensitivity reactions, including allergy, anaphylaxis, anemias, granulomas, and various skin responses. This is accompanied by identification, prevention, and treatment. The final discussion of preventing transplant rejection is preceded by a detailed unit on antibody technology and the testing methods for incompatibility.
DS
the course demands the application of the other two courses. the material was sufficient. Prof. Novotny was really good and funny.
SS
The best and concise course on the important fundamental immunological process.
GS
Very useful go me and I had gain more knowledge from u
ZF
Highly recommended to Biology and Life Science students.I liked the enthusiastic way of teaching from Dr. AlmaIf you have a small interest, go ahead.
NE
Was a very interesting course that added more to what i already know about Immunology, in a different perspective and innovative, effective approaches
BR
Wonderful course and Dr. Novotny is a passionate and engaging speaker. Thank you!
DV
Interesting course and more informative. Thank for Teacher
RJ
Excellent course. Dr. Novotny is an excellent teacher who uses well designed models...learnt so much!
HK
​such an amazing course thank you for your effort
SI
Excellent lecture and a very good content and a brilliant and funny lecturer.
CS
Content is very good but many quizzes have errors and there is no instructor responses in the discussion forum.
SN
Great course! Very well organized lectures. However, there are a few issues in the quizzes where some questions and options seem to be mixed up.
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This course connects the knowledge points introduced in the previous two courses, offers a systematic overview of immunity from a cell level to an individual level, and provides information with clinical implication. The practice quiz has a few mistakes, but you can figure them out in the discussion forum. Overall, I recommend it!
the course demands the application of the other two courses. the material was sufficient. Prof. Novotny was really good and funny.
The best and concise course on the important fundamental immunological process.
Third course of lectures in a series that gives a great introduction to immunology. This is a more applied course compared to the two earlier courses, but I'd recommend starting with the earlier lecture series unless you have a prior grasp of immunology fundamentals.
Amazing course, brilliant lecturer, entertaining and fascinating presentation of complex material that contributes to quick memorization.
Dr. Novotny never failed to amaze me from the first course up to this last part of the series. This specialization provides a well-structured flow of thought that will help you digest the humungous amount of information and overwhelming terminologies inherent in the field.
I never had a professor like Dr Alma Mam. She has been excellent throughout the specialization course. Although I will have to go through all of this again to grasp the concept even better thanks for making it so smooth
Highly recommended to Biology and Life Science students.
I liked the enthusiastic way of teaching from Dr. Alma
If you have a small interest, go ahead.
I really like this course, it's a great chance to understand the complicated things in a simple and funny way
Excellent lecture and a very good content and a brilliant and funny lecturer.
Very interesting course with great insights into the field of immunology
Interesting course and more informative. Thank for Teacher
Great course! Very well organized lectures. However, there are a few issues in the quizzes where some questions and options seem to be mixed up.
I've been enjoying this specialization but I was disappointed in a number of problems with this one. Questions on quizzes were prior to the actual lesson those questions came from. Some of the quizzes had questions that were not topics from lectures and these questions were straight recall and not critical thinking. On the final, the same question appeared twice!
Are the videos transcribed using some thyp of AI? I kept having to stop the video to correct the transcript and this slowed me down. In addition, the overall course outline was lacking figures shown in the video even though figures were supposed to be in the outline. I had to copy a lot of these missing figures to put them together with the transcript for better understanding.
Excellent if you want to grasp factoids and learn concepts of immunology. I came searching for a holistic understanding of immunology through this specialization, and while I did learn, I felt that the courses failed to transition concepts and put everything together as a painting.
Evaluations focus on memorizing regurgitating minute factoids rather than learning. I find courses went progressively downhill after the first one, which was wonderful.
Immunology is very difficult and very interesting. A low bow to Professor Alma Moon Novotny. This is immunology at the cosmic level!!!
I received confirmation of many theories that I assumed. Now I'm sure of them. I don't know the language well, it was difficult for me... but I did it!!! and I'm very proud of it! I just started teaching immunology and this knowledge was very valuable for me ... I will tell all this to my students...
I wish you good health and send you endless admiration, Professor!!!
Greetings from Russia!!! Svetlana Semiletova, candidate of biological Sciences, associate Professor
This was such an interesting course. I learned so much and it really highlighted the complexity of the immune system and autoimmune responses. I like that we get to learn about the type of assays and therapies used in immunology. Very insightful.
This is a fantastic course to take for those wanting to get better acquainted with immunology, specifically with how immune cells are involved with situations like allergies, autoimmune disorders, and graft-versus-host disease.
The coursera was wonderfull, the teacher is very didact and nice. Thanks Cousera and Tanks RIce Uniersity
Excellent course. Dr. Novotny is an excellent teacher who uses well designed models...learnt so much!