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Learner Reviews & Feedback for Experimental Methods in Systems Biology by Icahn School of Medicine at Mount Sinai

4.5
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314 ratings

About the Course

Learn about the technologies underlying experimentation used in systems biology, with particular focus on RNA sequencing, mass spec-based proteomics, flow/mass cytometry and live-cell imaging. A key driver of the systems biology field is the technology allowing us to delve deeper and wider into how cells respond to experimental perturbations. This in turns allows us to build more detailed quantitative models of cellular function, which can give important insight into applications ranging from biotechnology to human disease. This course gives a broad overview of a variety of current experimental techniques used in modern systems biology, with focus on obtaining the quantitative data needed for computational modeling purposes in downstream analyses. We dive deeply into four technologies in particular, mRNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging. These techniques are often used in systems biology and range from genome-wide coverage to single molecule coverage, millions of cells to single cells, and single time points to frequently sampled time courses. We present not only the theoretical background upon which these technologies work, but also enter real wet lab environments to provide instruction on how these techniques are performed in practice, and how resultant data are analyzed for quality and content....

Top reviews

CB

May 23, 2020

excellent overview of experimental methods in systems biology

TG

Jul 27, 2022

This was a very interesting course. I learned so much about the different techniques and methods. Also, you need to revise the lecture notes before taking the quizzes, because they can get tricky.

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51 - 55 of 55 Reviews for Experimental Methods in Systems Biology

By SYED A M H

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Jun 11, 2022

Very uusefu

By Weidong X

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Dec 3, 2016

good.

By Pooja P

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Aug 15, 2016

The course was very interesting. It touched upon all currently employed techniques in good detail. The lab-based videos were the most interesting. However, the lectures were too long. It would be a brilliant course if the lectures were cut short and made to the point.

By Rohaina T

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Sep 29, 2016

The questions based on the lectures are quite different and confusing

By Alison P

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Apr 16, 2018

quiz 5 from week 6 does not work.