Pr Shahragim Tajbakhsh

Head of the stem cells and development lab


The research of the Tajbakhsh laboratory focuses on identifying and characterizing skeletal muscle stem cells. His lab aims to characterize stem cells, and their daughters, during embryonic and postnatal development of skeletal muscle to understand how this tissue is established, and how it regenerates during disease, and after injury. They are examining the genetic networks, which regulate myogenic stem cell emergence, and relating this to how cell order is established in this lineage. They are also investigating how stem/progenitor cells self-renew, essentially via symmetric vs. asymmetric cell divisions, and how the stem cell niche is defined. With the participations of: Shahragim Tajbakhsh (Institut Pasteur, France), François Schweisguth (Institut Pasteur, France), Marc Van de Wetering (Princess Maxima Center for Pediatric Oncology, Netherlands), Allison Bardin (Institut Curie, France), Ana Cumano (Institut Pasteur, France), Philippe Herbomel (Institut Pasteur, France), Pierre-Marie Lledo (Institut Pasteur, France), Matthias Lutolf (EPFL, Switzerland), Sigolène Meilhac (Institut Pasteur, Institut Imagine, France) Laurence Daheron (Harvard Stem Cell Institute, USA), Kat Hadjantonakis (Sloan Kettering Institute, USA), Jenny Nichols (Cambridge Stem Cell Institute, UK), Alfonso Martinez Arias (University of Cambridge, UK), Emmanuelle Rial-Sebbag (Inserm, France)