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540 ratings

Yan Zhang +1 more instructor

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Advanced Neurobiology I

Peking University

About this Course

34,598 recent views

Hello everyone! Welcome to advanced neurobiology!
Neuroscience is a wonderful branch of science on how our brain perceives the external world, how our brain thinks, how our brain responds to the outside of the world, and how during disease or aging the neuronal connections deteriorate. We’re trying to understand the molecular, cellular nature and the circuitry arrangement of how nervous system works.

Through this course, you'll have a comprehensive understanding of basic neuroanatomy, electral signal transduction, movement and several diseases in the nervous system. 

This advanced neurobiology course is composed of 2 parts (Advanced neurobiology I and Advanced neurobiology II, and the latter will be online later). They are related to each other on the content but separate on scoring and certification, so you can choose either or both. It’s recommended that you take them sequentially and it’s great if you’ve already acquired a basic understanding of biology.

Thank you for joining us!

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Earn a Certificate upon completion

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Coursera Labs

Includes hands on learning projects.

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Intermediate Level

Approx. 27 hours to complete

English

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Flexible deadlines

Reset deadlines in accordance to your schedule.

Shareable Certificate

Earn a Certificate upon completion

100% online

Start instantly and learn at your own schedule.

Coursera Labs

Includes hands on learning projects.

Learn more about Coursera Labs

Intermediate Level

Approx. 27 hours to complete

English

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Instructors

Instructor rating

4.01/5 (72 Ratings)

Yan Zhang

Professor

School of Life Sciences, Peking University

60,800 Learners

2 Courses

Yulong Li

Research Fellow

School of Life Sciences, Peking University

56,790 Learners

1 Course

Offered by

Peking University

Peking University is determined to make its education openly accessible to students in China and around the world. With over 3000 faculty members, Peking University offers excellence in teaching and learning.

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Syllabus - What you will learn from this course

Content Rating89%(3,658 ratings)

Week1

Week 1

5 hours to complete

Anatomy of the Nervous System

5 hours to complete

32 videos (Total 230 min), 1 reading, 2 quizzes

32 videos

Welcome to Advanced Neurobilology!1m1.1.1 Terminology4m1.1.2 Central nervous system and blood brain barrier4m1.1.3 Meninges3m1.1.4 Telencephalon9m1.1.5 The localization and globalization theory12m1.1.6 White matter3m1.1.7 Internal structures11m1.1.8 Hippocampus and LTP13m1.1.9 Cerebellum3m1.2.1 Brain stem9m1.2.2 Cranial nerves13m1.2.3 Ascending and descending tracts and reticular formation2m1.2.4 Pons37s1.2.5 Reflex and reflex arc3m1.2.6 Concepts in the CNS and PNS2m1.2.7 Spinal cord8m1.2.8 The visceral nervous system12m1.2.9 Several pathways of the nervous system5m1 神经科学引言14m2 神经科学与人类健康和医药工业7m3 神经科学的启蒙时代7m4 神经科学的问题、方法、层次2m5 脑的功能分区：颅相学与Broca’s area9m6 脑的功能分区：皮层的分区6m7 脑的功能分区：两半球的差别7m8 PET和fMRI13m9 外周神经系统1m10 神经元学说和神经元极性3m11 神经环路1m12 神经信息传递：动作电位9m13 神经信息传递-化学传递18m

1 reading

Slides are available both in video and adneuro@outlook.com10m

2 practice exercises

Quiz 1.130mQuiz 1.230m

Week2

Week 2

4 hours to complete

Morphology of the neuronal cell & Cellular and Molecular Biology of the Neuron

4 hours to complete

19 videos (Total 160 min)

19 videos

2.1 Reductionism and hypothesis4m2.2 Morphology of the neuron5m2.3 Visualization of neurons and the neuron doctrine11m2.4 The story of the fluorescent proteins6m2.5 Stories of the Nobel prize13m2.6 Organic fluorescent probes2m2.7 Proteins specifically expressed in neurons and "brainbow" technique3m2.8 Microscopy techniques I14m2.9 Microscopy techniques II11m2.10 The electron microscope18m2.11 Glia and myelination3m2.12 Research: AIS and Ankyrin G14m3.1.1 A overview of neurons5m3.1.2 Real life situation: Aβ in Alzheimer’s disease8m3.1.3 Organelles and cytoskeleton in neurons8m3.1.4 Research: induction of the tunneling nanotube7m3.1.5 Defects in myelination and related diseases3m3.1.6 Synthesis and trafficking of neuronal proteins I10m3.1.7 Synthesis and trafficking of neuronal proteins II8m

2 practice exercises

Quiz 230mQuiz 3.130m

Week3

Week 3

3 hours to complete

Cellular and Molecular Biology of the Neuron

3 hours to complete

16 videos (Total 127 min)

16 videos

3.2.1 Cellular information transfer4m3.2.2 Signaling molecules3m3.2.3 Neurotransmitters and receptors7m3.2.4 The synapse4m3.2.5 Types of receptors14m3.2.6 Crosstalk of cellular signal transduction pathways2m3.2.7 The LTP11m3.2.8 The molecular mechanism of learning and memory11m3.2.9 Glia in a synapse2m3.3.1 Alzheimer’s disease: introduction and myths15m3.3.2 Alzheimer’s disease: pathology7m3.3.3 Parkinson’s disease: introduction52s3.3.4 Parkinson’s disease: symptoms and prognosis9m3.3.5 Parkinson’s disease: pathology3m3.3.6 Parkinson’s disease: treatment15m3.3.7 Prion diseases14m

2 practice exercises

Quiz 3.230mQuiz 3.330m

Week4

Week 4

6 hours to complete

Signaling within neurons & Ion channels and membrane potentials

6 hours to complete

30 videos (Total 263 min), 2 readings, 2 quizzes

30 videos

4.1 Overview9m4.2 The resting potential13m4.3 The resting potential and the Nernst equation13m4.4 The Nernst Equation11m4.5 Biological and electrical proporties of neurons I15m4.6 Biological and electrical proporties of neurons II4m4.7 Biological and electrical proporties of neurons III.18m5.1 Ion channels and membrane potentials I15m5.2 Ion channels and membrane potentials II5m5.3 Ion channels and membrane potentials III10m5.4 Ion channels and membrane potentials IV6m5.5 Ion channels and membrane potentials V10m5.6 Ion channels and membrane potentials VI10m5.7 Ion channels and membrane potentials VII15m5.8 Ion channels and membrane potentials VIII14mKang Shen - 16mKang Shen - 27mKang Shen -35mKang Shen - 44mKang Shen - 55mKang Shen - 66mKang Shen - 75mKang Shen - 82mLiqun Luo - 17mLiqun Luo - 28mLiqun Luo - 37mLiqun Luo - 44mLiqun Luo - 55mLiqun Luo - 66mLiqun Luo - 74m

2 readings

Lab page of Dr. Kang Shen10mLab page of Dr. Liqun Luo10m

2 practice exercises

Quiz 430mQuiz 530m

Week5

Week 5

2 hours to complete

Ion channels, membrane potential and synaptic transmission

2 hours to complete

8 videos (Total 94 min)

8 videos

6.1 Voltage sensing15m6.2 The Na+ gating current8m6.3 Inactivation gates17m6.4 Ion channel, membrane potential and synaptic transmission I15m6.5 Ion channel, membrane potential and synaptic transmission II7m6.6 Ion channel, membrane potential and synaptic transmission III12m6.7 Ion channel, membrane potential and synaptic transmission IV7m6.8 Ion channel, membrane potential and synaptic transmission V9m

1 practice exercise

Quiz 630m

Week6

Week 6

3 hours to complete

Neurotransmitter release

3 hours to complete

14 videos (Total 148 min)

14 videos

7.1 How does Ca2+ control neurotransmitter release I8m7.2 How does Ca2+ control neurotransmitter release II11m7.3 How does Ca2+ control neurotransmitter release III7m7.4 How does Ca2+ control neurotransmitter release IV10m7.5 Molecular mechanism involved in neurotransmetter release I7m7.6 Molecular mechanism involved in neurotransmetter release II7m7.7 Molecular mechanism involved in neurotransmetter release III5m7.8 Molecular mechanism involved in neurotransmetter release IV11m7.9 Molecular mechanism involved in neurotransmetter release V14m7.10 Molecular mechanism involved in neurotransmetter release VI12m7.11 Molecular mechanism involved in neurotransmetter release VII17m7.12 Molecular mechanism involved in neurotransmetter release VIII12m7.13 Molecular mechanism involved in neurotransmetter release IX7m7.14 Molecular mechanism involved in neurotransmetter release X13m

1 practice exercise

Quiz 730m

Week7

Week 7

3 hours to complete

Synaptic transmission & Synapitic plasticity

3 hours to complete

12 videos (Total 140 min)

12 videos

8.1 Synaptic trasmission I11m8.2 Synaptic trasmission II10m8.3 Synaptic trasmission III16m8.4 Synaptic transmission IV15m8.5 Synaptic trasmission V6m8.6 Synaptic trasmission VI13m9.1 Synapitic plasticity I13m9.2 Synapitic plasticity II8m9.3 Synapitic plasticity III12m9.4 Synapitic plasticity IV15m9.5 Synapitic plasticity V10m9.6 Synapitic plasticity VI7m

2 practice exercises

Quiz 830mQuiz 930m

Week8

Week 8

2 hours to complete

Techniques in neuroscience

2 hours to complete

6 videos (Total 66 min)

Reviews

4.1

133 reviews

5 stars
56.11%
4 stars
18.88%
3 stars
9.81%
2 stars
6.66%
1 star
8.51%

TOP REVIEWS FROM ADVANCED NEUROBIOLOGY I

by RSOct 23, 2017

Excellent information. Thank you for your recompilations and Time.

by JRMay 26, 2018

In depth with some topics. Lots of passion from the speaker. Most of the videos are just taped lectures. Some great interviews with Chinese top scientists

by RKMay 11, 2019

All information on this course is very useful for me. Now I can without any problem understand the hard themes in neurobiology. Thank you.

by JGJun 2, 2016

Fascinating course but a little too much math for my taste.

View all reviews

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When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
Is financial aid available?
Yes. In select learning programs, you can apply for financial aid or a scholarship if you can’t afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, you’ll find a link to apply on the description page.

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Advanced Neurobiology I

Advanced Neurobiology I

About this Course