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There are 4 modules in this course
Investigate the fundamental molecular and cellular mechanisms that govern life processes and human health. Build comprehensive understanding of how biological systems function at the molecular level to support clinical decision-making in nursing practice. Connect molecular principles to patient care scenarios through exploration of metabolism, genetics, and cellular communication pathways essential for understanding pharmacology and pathophysiology.
By the end of this course, you will be able to:
Analyze protein structure-function relationships, enzyme mechanisms, and their roles in cellular processes and drug interactions
Evaluate cellular membrane structure, transport mechanisms, and organelle functions that maintain cellular homeostasis
Explain energy metabolism pathways including glycolysis, Krebs cycle, and electron transport chain
Apply knowledge of cell cycle regulation, DNA replication, transcription, and translation to understand genetic disorders and therapeutic targets
Skills: Scientific Reasoning, Systems Thinking
Biochemistry is the study of biomolecules within living organisms. These compounds are found in every structure and process of every living species and appear to be key in the initiation and maintenance of life as we know it. In this course, the student will be introduced to the basic principles of biochemistry, including the most important concepts regarding carbohydrates, lipids, proteins, and nucleic acids. The levels of protein structures, gene expression, and basic metabolic functions will be covered as well. For optimal comprehension, the student will be required to be familiar with the basic notions of molecular and cellular biology.
What's included
72 videos12 readings73 assignments
Show info about module content
72 videos•Total 300 minutes
Overview•4 minutes
History•6 minutes
Structure•7 minutes
R-group Categories•2 minutes
Hydrophobic R-groups•6 minutes
Hydrophilic and Ionic R-groups•5 minutes
Ionization•7 minutes
Peptide Bonds•3 minutes
Polypeptides•4 minutes
Levels of Protein Structure and Primary Structure•3 minutes
Secondary Structure•8 minutes
Tertiary Structure•6 minutes
Quaternary Structure and Summary•3 minutes
Structure of Proteins•5 minutes
Globular Structural Proteins•2 minutes
Communication and Signaling•8 minutes
Involved Proteins•5 minutes
Antibodies•3 minutes
Gene Expression•4 minutes
Catalysis•5 minutes
Protein Transport•2 minutes
Oxygen Transport•5 minutes
Sodium-potassium ATPase•4 minutes
Saccharides•2 minutes
Common Sugars: Nomenclature & Structure•7 minutes
Cyclization & Cyclic Forms•7 minutes
Modified Sugars•2 minutes
Glycosides and Disaccharides•4 minutes
Polysaccharides•4 minutes
Lipid Links•3 minutes
Glycosaminoglycans•4 minutes
Protein Links•5 minutes
Peptidoglycans•3 minutes
Proteoglycans•3 minutes
Overview and Introduction on Fatty Acids•3 minutes
Fatty Acids•4 minutes
Glycerolipids and Glycerophospholipids•5 minutes
Sphingolipids•3 minutes
Polyketides•1 minute
Overview, Isoprenoids and Sterols•4 minutes
Steroid Hormones•3 minutes
Other Lipids and Their Function•6 minutes
Fat Soluble Vitamins•5 minutes
Structure of Membranes•1 minute
Lipid Bilayer•2 minutes
Bilayer Composition•6 minutes
Membrane Fluidity•2 minutes
Diffusion•5 minutes
Active Transport: Sodium-potassium Atpase•5 minutes
Active Transport: Sodium-calcium Exchanger•3 minutes
Transporter and Transport Proteins Types•3 minutes
Ion Channel•6 minutes
Ion Channel Blocker and Opener•5 minutes
Nucleotides•4 minutes
Structure and Topology of DNA•5 minutes
DNA Replication•1 minute
Transcription•6 minutes
Messenger RNAs•4 minutes
Structure of TRNA and RRNA•6 minutes
Genetic Code•5 minutes
TRNA Charging and Ribosomes•2 minutes
Translation•4 minutes
Energy Considerations•6 minutes
Metabolism•7 minutes
Oxidation and Reduction•3 minutes
Electron Carriers•3 minutes
Catabolism and Anabolism•4 minutes
Metabolic Pathways•3 minutes
Regulation of Enzymatic Activity•5 minutes
Allosterism•3 minutes
Covalent Modification•3 minutes
Gene Expression•3 minutes
12 readings•Total 360 minutes
Introduction to Biochemistry•30 minutes
Amino Acids•30 minutes
Peptides•30 minutes
Protein Movement and Cell Signaling•30 minutes
Protein Functions•30 minutes
Simple Carbohydrates•30 minutes
Complex Carbohydrates•30 minutes
Lipids•30 minutes
Biological Membranes•30 minutes
DNA, RNA and the Genetic Code•30 minutes
Oxidation and Reduction in Metabolism•30 minutes
Metabolism and Regulation•30 minutes
73 assignments•Total 390 minutes
Biochemistry: Basics – Final Quiz•30 minutes
Overview: Quiz•5 minutes
History: Quiz•5 minutes
Structure: Quiz•5 minutes
R-group Categories: Quiz•5 minutes
Hydrophobic R-groups: Quiz•5 minutes
Hydrophilic and Ionic R-groups: Quiz•5 minutes
Ionization: Quiz•5 minutes
Peptide Bonds: Quiz•5 minutes
Polypeptides: Quiz•5 minutes
Levels of Protein Structure and Primary Structure: Quiz•5 minutes
Secondary Structure: Quiz•5 minutes
Tertiary Structure: Quiz•5 minutes
Quaternary Structure and Summary: Quiz•5 minutes
Structure of Proteins: Quiz•5 minutes
Globular Structural Proteins: Quiz•5 minutes
Communication and Signaling: Quiz•5 minutes
Involved Proteins: Quiz•5 minutes
Antibodies: Quiz•5 minutes
Gene Expression: Quiz•5 minutes
Catalysis: Quiz•5 minutes
Protein Transport: Quiz•5 minutes
Oxygen Transport: Quiz•5 minutes
Sodium-potassium ATPase: Quiz•5 minutes
Saccharides: Quiz•5 minutes
Common Sugars: Nomenclature & Structure: Quiz•5 minutes
Cyclization & Cyclic Forms: Quiz•5 minutes
Modified Sugars: Quiz•5 minutes
Glycosides and Disaccharides: Quiz•5 minutes
Polysaccharides: Quiz•5 minutes
Lipid Links: Quiz•5 minutes
Glycosaminoglycans: Quiz•5 minutes
Protein Links: Quiz•5 minutes
Peptidoglycans: Quiz•5 minutes
Proteoglycans: Quiz•5 minutes
Overview and Introduction on Fatty Acids: Quiz•5 minutes
Fatty Acids: Quiz•5 minutes
Glycerolipids and Glycerophospholipids: Quiz•5 minutes
Sphingolipids: Quiz•5 minutes
Polyketides: Quiz•5 minutes
Overview, Isoprenoids and Sterols: Quiz•5 minutes
Steroid Hormones: Quiz•5 minutes
Other Lipids and Their Function: Quiz•5 minutes
Fat Soluble Vitamins: Quiz•5 minutes
Structure of Membranes: Quiz•5 minutes
Lipid Bilayer: Quiz•5 minutes
Bilayer Composition: Quiz•5 minutes
Membrane Fluidity: Quiz•5 minutes
Diffusion: Quiz•5 minutes
Active Transport: Sodium-potassium Atpase: Quiz•5 minutes
Active Transport: Sodium-calcium Exchanger: Quiz•5 minutes
Transporter and Transport Proteins Types: Quiz•5 minutes
Ion Channel: Quiz•5 minutes
Ion Channel Blocker and Opener: Quiz•5 minutes
Nucleotides: Quiz•5 minutes
Structure and Topology of DNA: Quiz•5 minutes
DNA Replication: Quiz•5 minutes
Transcription: Quiz•5 minutes
Messenger RNAs: Quiz•5 minutes
Structure of TRNA and RRNA: Quiz•5 minutes
Genetic Code: Quiz•5 minutes
TRNA Charging and Ribosomes: Quiz•5 minutes
Translation: Quiz•5 minutes
Energy Considerations: Quiz•5 minutes
Metabolism: Quiz•5 minutes
Oxidation and Reduction: Quiz•5 minutes
Electron Carriers: Quiz•5 minutes
Catabolism and Anabolism: Quiz•5 minutes
Metabolic Pathways: Quiz•5 minutes
Regulation of Enzymatic Activity: Quiz•5 minutes
Allosterism: Quiz•5 minutes
Covalent Modification: Quiz•5 minutes
Gene Expression: Quiz•5 minutes
Cellular Structure
Module 2•9 hours to complete
Module details
Cellular functioning, movement, and communication rely on the cytoskeleton, a large internal network of protein filaments embedded in the cytosol and anchored to the cell membrane. In this course, the student will be introduced to the composition and function of the cytoskeleton, mechanisms of molecular transport, modes of cell communication, and second messengers. For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology and chemistry.
What's included
29 videos7 readings30 assignments
Show info about module content
29 videos•Total 128 minutes
Introduction to the Cellular Structure•4 minutes
Nucleus and Ribosomes•4 minutes
Endomembrane System•2 minutes
Endoplasmic Reticulum and Golgi Apparatus•3 minutes
Lysosomes•3 minutes
Mitochondria and Origins of Eukaryotic Cells•4 minutes
Introduction to Membranes•1 minute
Fluid Mosaic Model•5 minutes
Role of Cell Membrane Proteins•4 minutes
How Proteins Anchor Themselves in the Membrane•3 minutes
Passive Transport•7 minutes
Osmosis and Tonicity•8 minutes
Active Transport•8 minutes
Bulk Transport•5 minutes
Cytoskeleton•5 minutes
Transport and Network of Proteins•3 minutes
Extracellular Structures and Cell Movement•3 minutes
Cell Identity•3 minutes
Three Types of Cell Junctions•5 minutes
Introduction•3 minutes
Modes of Cell Communication: Overview•6 minutes
Phosphorylation•3 minutes
Cell Surface Receptors•5 minutes
Intracellular Receptors•5 minutes
Overview•2 minutes
Second Messenger Systems: Definition•4 minutes
Receptor Tyrosine Kinase Pathways•13 minutes
G-protein Coupled Receptors•8 minutes
Recap•3 minutes
7 readings•Total 210 minutes
The Blueprint of the Cell•30 minutes
The Dynamic Cell Membrane•30 minutes
Transport Across Cell Membranes•30 minutes
Cellular Scaffolding and Movement•30 minutes
Establishing Identity and Connections•30 minutes
Introduction to Cell Communication•30 minutes
Second Messengers and Signaling Pathways•30 minutes
30 assignments•Total 175 minutes
Cellular Structure – Final Quiz•30 minutes
Introduction to the Cellular Structure: Quiz•5 minutes
Nucleus and Ribosomes: Quiz•5 minutes
Endomembrane System: Quiz•5 minutes
Endoplasmic Reticulum and Golgi Apparatus: Quiz•5 minutes
Lysosomes: Quiz•5 minutes
Mitochondria and Origins of Eukaryotic Cells: Quiz•5 minutes
Introduction to Membranes: Quiz•5 minutes
Fluid Mosaic Model: Quiz•5 minutes
Role of Cell Membrane Proteins: Quiz•5 minutes
How Proteins Anchor Themselves in the Membrane: Quiz•5 minutes
Passive Transport: Quiz•5 minutes
Osmosis and Tonicity: Quiz•5 minutes
Active Transport: Quiz•5 minutes
Bulk Transport: Quiz•5 minutes
Cytoskeleton: Quiz•5 minutes
Transport and Network of Proteins: Quiz•5 minutes
Extracellular Structures and Cell Movement: Quiz•5 minutes
Cell Identity: Quiz•5 minutes
Three Types of Cell Junctions: Quiz•5 minutes
Introduction: Quiz•5 minutes
Modes of Cell Communication: Overview: Quiz•5 minutes
Phosphorylation: Quiz•5 minutes
Cell Surface Receptors: Quiz•5 minutes
Intracellular Receptors: Quiz•5 minutes
Overview: Quiz•5 minutes
Second Messenger Systems: Definition: Quiz•5 minutes
Receptor Tyrosine Kinase Pathways: Quiz•5 minutes
G-protein Coupled Receptors: Quiz•5 minutes
Recap: Quiz•5 minutes
Cell Cycle and Cell Division
Module 3•7 hours to complete
Module details
Cells, as the fundamental unit of living organisms, also have a life cycle. The cell cycle is a series of phases a cell undergoes to reach division into a new generation of cells and perpetuate its genetic material. Each phase encapsulates different processes required to ensure the daughter cells are well equipped to begin their own cycles after division. In this course, the student will be given a walkthrough of the phases of the cell cycle and all the processes that take place during each one, finishing with a discussion of diploid and haploid cell division. For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology and chemistry.
What's included
22 videos6 readings23 assignments
Show info about module content
22 videos•Total 75 minutes
Introduction•3 minutes
Cell Cycle Controls•9 minutes
Growth Factors•3 minutes
P53 Gene•3 minutes
Mutated Genes•5 minutes
Two Hit Hypothesis•3 minutes
Overview•1 minute
Language of Chromosomes•3 minutes
Eukaryotic Chromosomes•3 minutes
Cell Division•2 minutes
Interphase and Prophase•2 minutes
Prometaphase, Metaphase and Anaphase•4 minutes
Telophase and Cytokinesis•5 minutes
Introduction and Reduce of Chromosomes•6 minutes
Homologous Chromosome Pairs•3 minutes
Human Karyotype•1 minute
Meiosis I: Prophase I•2 minutes
Meiosis I: Metaphase I•4 minutes
Meiosis I: Anaphase I and Telophase I•2 minutes
Meiosis II: Phases•4 minutes
Meiosis in Humans•3 minutes
Comparing Mitosis and Meiosis – Cell Division•4 minutes
6 readings•Total 180 minutes
Setting the Stage – Cell Cycle and Its Regulation•30 minutes
When Control Fails – Cancer-Related Genes•30 minutes
Mitosis – The Mechanics of Cell Division•30 minutes
Chromosomes and Reduction Division•30 minutes
Meiosis – Creating Diversity•30 minutes
Mitosis vs. Meiosis – Comparing the Strategies•30 minutes
23 assignments•Total 140 minutes
Cell Cycle and Cell Division – Final Quiz•30 minutes
Introduction: Quiz•5 minutes
Cell Cycle Controls: Quiz•5 minutes
Growth Factors: Quiz•5 minutes
P53 Gene: Quiz•5 minutes
Mutated Genes: Quiz•5 minutes
Two Hit Hypothesis: Quiz•5 minutes
Overview: Quiz•5 minutes
Language of Chromosomes: Quiz•5 minutes
Eukaryotic Chromosomes: Quiz•5 minutes
Cell Division: Quiz•5 minutes
Interphase and Prophase: Quiz•5 minutes
Prometaphase, Metaphase and Anaphase: Quiz•5 minutes
Telophase and Cytokinesis: Quiz•5 minutes
Introduction and Reduce of Chromosomes: Quiz•5 minutes
Homologous Chromosome Pairs: Quiz•5 minutes
Human Karyotype: Quiz•5 minutes
Meiosis I: Prophase I: Quiz•5 minutes
Meiosis I: Metaphase I: Quiz•5 minutes
Meiosis I: Anaphase I and Telophase I: Quiz•5 minutes
Meiosis II: Phases: Quiz•5 minutes
Meiosis in Humans: Quiz•5 minutes
Comparing Mitosis and Meiosis – Cell Division: Quiz•5 minutes
Energy, Enzymes and Metabolism
Module 4•9 hours to complete
Module details
All organisms require energy to function. By utilizing energy, living organisms oppose the breakdown of their systems brought about by contact with the external environment. Energy is extracted from biomolecules by cells via catabolic pathways and cellular respiration. In this course, the student will be introduced to the cellular processes of energy synthesis in the form of adenosine triphosphate (ATP). For optimal comprehension, the student will be required to be familiar with the basic concepts of college-grade biology, chemistry, and physics, with an emphasis on the laws of thermodynamics.
What's included
25 videos8 readings27 assignments
Show info about module content
25 videos•Total 84 minutes
Definition of Energy•3 minutes
Laws of Thermodynamics•4 minutes
Chemical, Endergonic and Exergonic Reactions•4 minutes
Activation Energy of Reactions•2 minutes
Bicarbonate Buffering System•4 minutes
ATP – Adenosine Triphosphate•2 minutes
Electrochemical Gradient•4 minutes
ATP Synthase•3 minutes
Activation and Inhibition•3 minutes
Assisting Enzymes•2 minutes
Biochemical Pathways•3 minutes
Metabolic Pathways•4 minutes
Process of Metabolism•4 minutes
Overview•7 minutes
A Review of Glycolysis•2 minutes
Pyruvate Oxidation•2 minutes
Anaerobic Glycolysis•4 minutes
Recycling of NADH•2 minutes
Krebs Cycle•7 minutes
Electron Transport Chain (ETC)•2 minutes
Electron Transport Chain (ETC) and Chemiosmosis•2 minutes
Introduction•1 minute
Entry Points into Cellular Respiration•2 minutes
Catabolism of Fats and Proteins•4 minutes
Cell Respiration•6 minutes
8 readings•Total 240 minutes
Nature of Energy and Life•30 minutes
How Reactions Happen•30 minutes
ATP – The Energy Currency•30 minutes
Enzymes – Catalysts of Life•30 minutes
Metabolic Pathways – The Cell’s Roadmaps•30 minutes
Glycolysis and Pyruvate Oxidation•30 minutes
Krebs Cycle and Electron Transport•30 minutes
Metabolism in Context•30 minutes
27 assignments•Total 245 minutes
Energy, Enzymes and Metabolism – Final Quiz•30 minutes
Project: "Cellular Process Analysis"•90 minutes
Definition of Energy: Quiz•5 minutes
Laws of Thermodynamics: Quiz•5 minutes
Chemical, Endergonic and Exergonic Reactions: Quiz•5 minutes
Activation Energy of Reactions: Quiz•5 minutes
Bicarbonate Buffering System: Quiz•5 minutes
ATP – Adenosine Triphosphate: Quiz•5 minutes
Electrochemical Gradient: Quiz•5 minutes
ATP Synthase: Quiz•5 minutes
Activation and Inhibition: Quiz•5 minutes
Assisting Enzymes: Quiz•5 minutes
Biochemical Pathways: Quiz•5 minutes
Metabolic Pathways: Quiz•5 minutes
Process of Metabolism: Quiz•5 minutes
Overview: Quiz•5 minutes
A Review of Glycolysis: Quiz•5 minutes
Pyruvate Oxidation: Quiz•5 minutes
Anaerobic Glycolysis: Quiz•5 minutes
Recycling of NADH: Quiz•5 minutes
Krebs Cycle: Quiz•5 minutes
Electron Transport Chain (ETC): Quiz•5 minutes
Electron Transport Chain (ETC) and Chemiosmosis: Quiz•5 minutes
Introduction: Quiz•5 minutes
Entry Points into Cellular Respiration: Quiz•5 minutes
Catabolism of Fats and Proteins: Quiz•5 minutes
Cell Respiration: Quiz•5 minutes
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