Neurohacking describes how to use the R programming language (https://cran.r-project.org/) and its associated package to perform manipulation, processing, and analysis of neuroimaging data. We focus on publicly-available structural magnetic resonance imaging (MRI). We discuss concepts such as inhomogeneity correction, image registration, and image visualization.
This course is part of the Neuroscience and Neuroimaging Specialization
Offered By
Neuroscience and Neuroimaging SpecializationJohns Hopkins UniversityAbout this Course
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Learner Career Outcomes
25%
started a new career after completing these courses
11%
got a tangible career benefit from this course
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Course 4 of 4 in the
Flexible deadlines
Reset deadlines in accordance to your schedule.
Intermediate Level
Approx. 18 hours to complete
English
Subtitles: French, Portuguese (Brazilian), Russian, English, Spanish
Skills you will gain
Image ProcessingBrainR ProgrammingNeurology
Learner Career Outcomes
25%
started a new career after completing these courses
11%
got a tangible career benefit from this course
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Course 4 of 4 in the
Flexible deadlines
Reset deadlines in accordance to your schedule.
Intermediate Level
Approx. 18 hours to complete
English
Subtitles: French, Portuguese (Brazilian), Russian, English, Spanish
Offered by
Johns Hopkins University
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
Syllabus - What you will learn from this course
1 hour to complete
Introduction
1 hour to complete
3 videos (Total 30 min), 1 reading, 1 quiz
1 reading
Syllabus10m
1 practice exercise
Theme 1 Quiz30m
4 hours to complete
Neuroimaging: Formats and Visualization
In this section, we will discuss different formats that brain images come in, as well as some of the commonly done magnetic resonance imaging (MRI) scans.
4 hours to complete
7 videos (Total 74 min)
7 videos
The NIfTI Format9m
Basic Visualization 19m
Basic Visualization 29m
Basic Data Manipulation9m
Transformations and Smoothing14m
Basic MRI Contrasts9m
6 practice exercises
Theme 2 Lecture 1 Quiz30m
Theme 2 Lecture 2 Quiz30m
Theme 2 Lecture 3 Quiz30m
Theme 2 Lecture 4 Quiz30m
Theme 2 Lecture 5 Quiz30m
Theme 2 Lecture 6 Quiz30m
6 hours to complete
Image Processing
In this section, we will discuss the steps done to process brain MRI data. We will discuss inhomogeneity correction, brain extraction or skull stripping, and various image registration techniques.
6 hours to complete
9 videos (Total 71 min)
9 videos
Registration15m
fslr: System Requirements8m
Bias Field Correction Using fslr3m
Brain Extraction using fslr5m
Image Registration Using fslr5m
Installing ANTsR5m
Basic Data Manipulation with ANTsR4m
Pre-Processing with ANTSR7m
9 practice exercises
Theme 3 Quiz 130m
Theme 3 Quiz 230m
Theme 3 Quiz 330m
Theme 3 Quiz 430m
Theme 3 Quiz 530m
Theme 3 Quiz 630m
Theme 3 Quiz 730m
Theme 3 Quiz 830m
Theme 3 Quiz 930m
7 hours to complete
Extended Image Processing
In this section, we will discuss the different types of registration and how one would go through processing a multi-sequence MRI scan, as well as wrapper functions that make the process much easier. We also cover interactive exploration of brain image data and tissue-level (white/gray matter and cerebrospinal fluid (CSF)) segmentation from a T1-weighted image.
7 hours to complete
11 videos (Total 101 min), 1 reading, 10 quizzes
11 videos
Co-Registration using fslr9m
Co-Registration using ANTsR9m
Wrapper Functions for Processing Pipelines8m
Across-Visit Co-Registration of T1 Images6m
Rigid Registration to a Template8m
Affine Registration of T1 to Template4m
Nonlinear Registration of T1 to Template6m
Getting ROI Anatomic Information from Non-Linear Registration12m
Tissue-Level Segmentation7m
Papayar: Interactively Viewing Images in R22m
1 reading
Papayar Script10m
10 practice exercises
Theme 4 Quiz 130m
Theme 4 Quiz 230m
Theme 4 Quiz 330m
Theme 4 Quiz 430m
Theme 4 Quiz 530m
Theme 4 Quiz 630m
Theme 4 Quiz 730m
Theme 4 Quiz 830m
Theme 4 Quiz 930m
Theme 4 Quiz 1030m
Reviews
TOP REVIEWS FROM INTRODUCTION TO NEUROHACKING IN R
by BRFeb 8, 2017
I like that this course goes through most necessary steps, my only suggest would be to have one additional week where you go through everything all together, and then do some simple group analysis.
by SJMay 7, 2019
Thank you for the wonderful course. Especially useful when the team explains every new line of code. As a current undergraduate and aspiring neuroscience researcher, this is tremendously helpful.
by SGAug 28, 2020
The process of downloading packages on the virtual machine was very tiring. The documentation of it could have been provided more nicely. Like I was not aware about the 'sudo...'on LINUX.
by ANJul 17, 2017
Perfect! Precise to the subject and provides a lot of hands-on details, which is, unfortunately, something that most other similar courses don't do. Absolutely loved it!
About the Neuroscience and Neuroimaging Specialization
This specialization combines the strength of 4 different neuroscience courses into a cohesive learning experience. Taught by Johns Hopkins University, it begins with fundamental neuroscience concepts for neuroimaging. Neuroimaging methods are used with increasing frequency in clinical practice and basic research. Starting with the neuroanatomy of the brain, it then moves into principles of neuroimaging, including experimental design in neuroimaging, functional connectivity MRI, diffusion tensor imaging and spectroscopy imaging.
Frequently Asked Questions
When will I have access to the lectures and assignments?
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
- The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
- The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
What will I get if I subscribe to this Specialization?
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
Is financial aid available?
Yes, Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You'll be prompted to complete an application and will be notified if you are approved. You'll need to complete this step for each course in the Specialization, including the Capstone Project. Learn more.
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