This course will provide you with the key knowledge and tools to understand the fundamentals and practical implications of precision medicine, its opportunities and challenges. It will address precision-medicine era diagnostics, treatment selection, genetic counseling, public health interventions, and biomedical research. It will also deal with data science and ethical issues.
Offered By
Precision Medicine
University of GenevaAbout this Course
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Intermediate Level
Approx. 29 hours to complete
English
Subtitles: English
Instructors
Shareable Certificate
Earn a Certificate upon completion
100% online
Start instantly and learn at your own schedule.
Flexible deadlines
Reset deadlines in accordance to your schedule.
Intermediate Level
Approx. 29 hours to complete
English
Subtitles: English
Offered by
University of Geneva
Founded in 1559, the University of Geneva (UNIGE) is one of Europe's leading universities. Devoted to research, education and dialogue, the UNIGE shares the international calling of its host city, Geneva, a centre of international and multicultural activities with a venerable cosmopolitan tradition.
Syllabus - What you will learn from this course
4 hours to complete
Monogenic Diseases
4 hours to complete
12 videos (Total 55 min), 4 readings, 6 quizzes
12 videos
Trailer1m
Welcome to the course3m
Introduction to the module2m
Human genome variabilty and phenotype consequences 11m
Human genome variability and phenotype consequences 24m
Medical consultation (part 1)8m
Exome sequencing analysis9m
What are the options? discussion between the physician and the biologist4m
Medical consultation (part 2)2m
Rare genetic disorder and precision medicine7m
Ethical, Legal and Social Implications (ELSI)6m
Conclusion1m
4 readings
How assessments work10m
Syllabus10m
List of Teachers10m
Bibliographic References10m
6 practice exercises
Human genome variability and phenotype consequences30m
Medical consultation part 130m
Exome sequencing analysis30m
Rare genetic disorder and precision medicine30m
Ethical, Legal and Social Implications (ELSI)30m
Monogenic disease22m
3 hours to complete
Complex Diseases
3 hours to complete
10 videos (Total 43 min)
10 videos
Genetics of complex disorders6m
Environmental determinant7m
Diabetes management today2m
Diabetes risk assessment part 110m
The key points - answers to the discussion by the expert (part 1)2m
Precision approaches in diabetes55s
Diabetes risk assessment (part 2)6m
The key points - answers to the discussion by the expert (part 2)2m
Conclusion2m
5 practice exercises
Genetics of complex disorders30m
Environmental determinants30m
How to evaluate the disease risk (part 1)30m
How to evaluate the disease risk (part 2)30m
Complex disease20m
3 hours to complete
Cancer
3 hours to complete
18 videos (Total 116 min), 1 reading, 17 quizzes
18 videos
Synthetic lethality and oncogene addiction5m
Clinically-orientated analysis6m
Introduction to clinical ethics9m
Objectives of precision oncology3m
Tumor classification4m
What is a biomarker?6m
Somatic bioinformatics pipelines9m
Molecular tumor board5m
Ethical and societal implications9m
Sporadic, familial and hereditary cancer5m
Family history in oncology4m
Genetic counselling in oncology10m
Main hereditary cancer syndromes9m
Case study 1 - part 15m
Case study 1 - part 26m
Case study 2 - part 15m
Case study 2 - part 23m
1 reading
Further reading10m
17 practice exercises
Sommatic mutation theory of cancer
Synthetic lethality and oncogene addiction
Introduction to clinical ethics
Objectives of precision oncology
Tumor classification
What is a biomarker?
Somatic bioinformatics pipeline30m
Molecular tumor board
Ethical and societal implications
Sporadic, familial and hereditary cancer
Family history in oncology
Genetic counselling in oncology
Main hereditary cancer syndromes2m
Case Study 1 - part 1
Case Study 1 - part 2
Case Study 2 - part 1
Cancer36m
4 hours to complete
Health and Prevention
4 hours to complete
13 videos (Total 66 min), 1 reading, 7 quizzes
13 videos
The Revolution of Genetic Technologies7m
Main Opportunities of Genomics1m
Genomics and Complex Chronic Diseases9m
The Revolution of Environmental Technologies7m
Genome-Exposome Interaction2m
Big Data6m
Validity and Massive Information4m
Restitution, Unintended Findings and Actionable Variants2m
Patients' Willingness to Discuss their Genomic Information2m
Evidence-Based Precision Medicine2m
Conclusion1m
New Technologies and Personalized Health: Opportunities and Challenges16m
1 reading
Tyrell and all.10m
7 practice exercises
Testing the opportunities discussed
Testing the illustration discussed30m
Testing the concept of behaviome
Testing the understanding of the Tyrell and all. results30m
Big Data30m
Testing challenges of translating genomics into clinical care30m
Health and prevention22m
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