Learn how the nervous system produces behavior, how we use our brain every day, and how neuroscience can explain the common problems afflicting people today. We will study functional human neuroanatomy and neuronal communication, and then use this information to understand how we perceive the outside world, move our bodies voluntarily, stay alive, and play well with others.
Understanding the Brain: The Neurobiology of Everyday Life
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Understanding the Brain: The Neurobiology of Everyday Life

Instructor: Peggy Mason
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There are 10 modules in this course
Neurobiology is a rapidly growing area of scientific research, and is becoming increasingly prevalent in the news and popular culture. In this course, we will study of the nervous system from a biological perspective by exploring the fundamental concepts in neurobiology, including how we sense the world, how we act in the world, and common neurological disorders.
What's included
17 videos3 readings1 assignment
17 videos•Total 85 minutes
- Introduction: The Bauby Story•6 minutes
- Ethics and Brain Science•1 minute
- I Am a Patient•1 minute
- The Four Functions•6 minutes
- Central Anatomy•7 minutes
- Meet the Stars: Neurons•2 minutes
- Parts of the Neuron•4 minutes
- Neuronal Uniqueness: Stars of the Sky•9 minutes
- Glial Cells•7 minutes
- Myelin•5 minutes
- Demyelinating Diseases•3 minutes
- Meninges•6 minutes
- Peripheral Diseases•6 minutes
- Brain Tumors•6 minutes
- The Brain and the Spinal Cord•3 minutes
- Meninges•7 minutes
- Brain Tumors•5 minutes
3 readings•Total 30 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Clinical Vignette: Brain Tumor•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 22 minutes
- The Nervous System•22 minutes
Neurons are the cells of the nervous system responsible for communicating, relaying, and integrating information. Neurons "talk" to other neurons through a special type of language that involves electrical signaling within individual neurons, and the use of chemical compounds known as neurotransmitters to communicate between neurons. In this module, you will learn more about how a neuron functions at rest, how information is relayed within a neuron, and how neurons relay information to other neurons or target tissues. In the second half of this module, you will be learning about how the body and emotions work together to produce our everyday emotional experiences. We will look at the enteric nervous system and learn how to discern whether the sympathetic or parasympathetic system is impacting our current emotional state.
What's included
17 videos3 readings1 assignment
17 videos•Total 99 minutes
- Electrical Language•8 minutes
- Electricity Review•4 minutes
- Action Potential•5 minutes
- Neurotransmitter Synthesis•5 minutes
- Neurotransmitter Release•6 minutes
- Clostridial Toxins: Botox•6 minutes
- Signal Termination•7 minutes
- Receptors•8 minutes
- Metabotropic Receptors•7 minutes
- Wrap-Up: Neurocommunication•2 minutes
- Introduction to Embodied Emotion•4 minutes
- Enteric Nervous System•6 minutes
- Parasympathetics & Sympathetics•7 minutes
- Parasympathetic/Sympathetic Balance•4 minutes
- Autonomic Pharmacology: Adjusting the PS/S System•7 minutes
- Spinal Cord Injury•8 minutes
- Wrap-Up: Embodied Emotion•6 minutes
3 readings•Total 30 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
- Optional Survey on MOOCs•10 minutes
1 assignment•Total 30 minutes
- Neurocommunications•30 minutes
Neuroanatomy tells us how the nervous system is organized. Understanding the form of the brain is essential to understanding its function. By comparing the structure of the brain with a patient's symptoms, neurologists are able to identify the location of certain disorders. Studying how the human brain develops provides insight to why it is organized as it is. This module, you will learn about how the brain develops during gestation, some major pathways in the nervous system, and what can go wrong!
What's included
26 videos2 readings1 assignment
26 videos•Total 206 minutes
- Introduction to Neuroanatomy•8 minutes
- Neural Tube Formation•5 minutes
- Neural Tube Defects•11 minutes
- Brain Vesicles•8 minutes
- Expansion of the Cerebral Cortex•12 minutes
- Two Forebrain Tracts•9 minutes
- Cerebral Palsy•10 minutes
- Nerves•11 minutes
- CNS Regional Functions•13 minutes
- Hemisphere Functions•4 minutes
- Aphasia•8 minutes
- Language Circuits•10 minutes
- Making a Flat Schematic of the Brain•5 minutes
- Oxygen and Cerebral Blood Flow•7 minutes
- Blood Supply•6 minutes
- Strokes and Tumors•8 minutes
- Bleeds•7 minutes
- Spinal Cord•8 minutes
- Inside the Cranium•6 minutes
- Telencephalon•5 minutes
- Cortex•8 minutes
- Cerebellum•6 minutes
- Visual Pathway•7 minutes
- Pituitary Tumors•6 minutes
- Blood Supply•10 minutes
- Hippocampus & Alzheimer's Disease•10 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resource•10 minutes
1 assignment•Total 30 minutes
- Neuroanatomy•30 minutes
Perception is how the brain interprets incoming stimuli. Not all stimuli that can be sensed are perceivable, and sometimes those that can be perceived play tricks on us. The systematic ways that stimuli are interpreted (or misinterpreted) show how well the brain can understand our surroundings, sometimes with limited information. This module we will explore perception and vision.This module contains a lot of material, so be sure to start early so that you have time to finish!
What's included
26 videos3 readings1 assignment
26 videos•Total 159 minutes
- Introduction to Perception•4 minutes
- Sensory Interpretation: Optical Illusions•4 minutes
- Sensory Interpretation: Auditory Illusions•3 minutes
- Sensory Interpretation: Weber's Law•4 minutes
- Stimulus Set•7 minutes
- The Road to Perception•5 minutes
- Name the Senses•5 minutes
- The Visual Pathway•4 minutes
- Distance Vision•4 minutes
- Near Vision + Near Triad•7 minutes
- Emmetropization•6 minutes
- Light Path•6 minutes
- Rods and Cones•9 minutes
- Central Vision•9 minutes
- Color Vision•8 minutes
- Visual Fields•9 minutes
- The Importance of Edges•6 minutes
- Visual Perception•8 minutes
- Learning to See•7 minutes
- Sheep Brain vs Human Brain•5 minutes
- Sheep Cerebellum•3 minutes
- Sheep Brain Parts•6 minutes
- Sheep Brainstem•5 minutes
- Sheep Ventricles, pt.1•4 minutes
- Sheep Ventricles, pt.2•12 minutes
- Sheep Spinal Cord & Cauda Equina•9 minutes
3 readings•Total 30 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Clinical Vignette: Albinism•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Perception and Vision•30 minutes
The sound of birds chirping in the morning, a babbling brook or crashing waves on the beach, or warm conversation with the ones you love. The experience of all these things requires the ability to hear. Arguably the most important sense for human communication, it is also the most commonly impaired of our senses. In this module, you will learn how the human ear is artfully designed to enhance our ability to hear the human voice. You will follow sound waves as they travel from the external world, to the eardrum, through the bones of the middle ear, and to the cochlea that transduces sound information into neural impulses.
What's included
16 videos3 readings1 assignment
16 videos•Total 80 minutes
- Introduction to Hearing•3 minutes
- Experiences of Hearing Loss•9 minutes
- Hearing Pathways•5 minutes
- External Ear•5 minutes
- Rinne Test•2 minutes
- Middle Ear•6 minutes
- Inner Ear•7 minutes
- Cochlear Amplifier•3 minutes
- Outer Hair Cell Motility•6 minutes
- Otoacoustic Emissions•3 minutes
- Hearing Loss•7 minutes
- Weber and Rinne•8 minutes
- Expectation: Interpreting Sound•4 minutes
- Prosody•6 minutes
- Communication•3 minutes
- Wrap-up: Hearing•2 minutes
3 readings•Total 30 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Clinical Vignette: One Man's Story of Hearing•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Hearing•30 minutes
The vestibular system and gaze control give us so much but are grossly under appreciated. They are so fundamental that we discount them, assuming that they will always be there. When the vestibular system fails us, its importance dominates our lives. Living with either a vestibular or an eye movement disorder is very disruptive to everyday life. In this module, you will learn how the inner ear is designed to detect and respond to head movements. You will learn about the circuit that connects the inner ear to the motoneurons that control the location of your eyes, allowing us to reflexively maintain our view of an object even as we move about in the world. Finally, we will talk about how you can modify this reflexive control of the eyes and how you can control where you are looking.
What's included
16 videos2 readings1 assignment
16 videos•Total 82 minutes
- Introduction to Vestibular Sense•4 minutes
- The Vestibular Stimulus•5 minutes
- Canals and Otoconial Masses•8 minutes
- Hair Cell Orientation•6 minutes
- Yoked End Organs, Part 1•5 minutes
- Yoked End Organs, Part 2•4 minutes
- Otoconial Disorders•6 minutes
- Visual Integration•4 minutes
- The VOR Is Fast•5 minutes
- Horizontal VOR Circuitry•5 minutes
- Nystagmus•5 minutes
- Adapting the VOR•5 minutes
- Eye Movements•5 minutes
- Saccades•6 minutes
- Saccade Circuits•5 minutes
- Controlling Saccades•6 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- The Vestibular Sense & Gaze•30 minutes
"Voluntary movements are how we interact with the world. The organization of the motor system has implications for how we move, and the types of movements we can make. This module we'll start to explore the organization of the motor system, from neurons to muscles. This module contains a lot of material, so be sure to start early so that you have time to finish!"
What's included
18 videos2 readings1 assignment
18 videos•Total 89 minutes
- Introduction to Voluntary Movement•3 minutes
- Motor Hierarchy•5 minutes
- Problems with Motor Hierarchy•5 minutes
- Motor Modulation•7 minutes
- Fast and Slow Fibers•5 minutes
- Motoneuron Types•4 minutes
- Orderly Recruitment•8 minutes
- Exercise and Muscle Mass•3 minutes
- Monosynaptic Reflex•5 minutes
- Co-activation•4 minutes
- Gamma Reflex Loop•5 minutes
- Posture•5 minutes
- Postural Control•6 minutes
- Central Pattern Generator•8 minutes
- Intro to Self-Generated Movements•3 minutes
- Praxis•4 minutes
- Emotional Movements•7 minutes
- Wrap-up•2 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Voluntary Movements•30 minutes
You should now have an understanding of how muscles function to initiate movements. However, the brain requires more than just the cerebral cortex to determine what movements to perform and to make those movements smooth and guided. This module, we'll explore the cerebellum and the basal ganglia, fascinating structures that play a major role in movement. You'll also learn how these brain regions are involved in motor learning and disease.
What's included
19 videos2 readings1 assignment
19 videos•Total 99 minutes
- The Data-Driven Cerebellum•6 minutes
- The Purkinje Cell•4 minutes
- Cerebellar Functions•6 minutes
- Cerebellar Topography•6 minutes
- Cerebellar Laterality•3 minutes
- Efference Copy and Sensory Reafference•6 minutes
- Cerebellar Learning and the VOR•8 minutes
- Extreme Vestibular Plasticity (optional) •4 minutes
- More Cerebellar Learning•6 minutes
- Action Selection•5 minutes
- Basal Ganglia Anatomy•2 minutes
- Basal Ganglia Pathways•8 minutes
- Basal Ganglia Experiment (optional)•2 minutes
- Operational Learning•6 minutes
- Chunking•7 minutes
- Parkinson's Disease•8 minutes
- Non-Motor Functions of Basal Ganglia•4 minutes
- Cerebellum and Basal Ganglia Cooperation•6 minutes
- Wrap-Up: Voluntary Movement, part 2•2 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Motor Modulation•30 minutes
Although our bodies are very robust and we can live in a range of environments, our brain requires very specific conditions to function properly. Homeostasis is the active process by which our nervous system regulates internal conditions, such as blood pressure and temperature. This module we will explore what homeostasis does, and how it functions in everyday life.
What's included
13 videos2 readings1 assignment
13 videos•Total 73 minutes
- Introduction to Homeostasis•3 minutes
- Hypothalamic Anatomy•4 minutes
- Pituitary Gland & Gigantism•5 minutes
- Post-Partum Mood Disorders•7 minutes
- Thermoregulation•9 minutes
- Hyperthermia•3 minutes
- Fever and Hot Flashes•10 minutes
- Breathing•5 minutes
- Urination•6 minutes
- Problems with the Urination System•6 minutes
- Sleep Phenomenology•7 minutes
- Sleep Mechanisms•6 minutes
- Wrap-Up: Homeostasis•2 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Homeostasis•30 minutes
You've now learned an incredible amount about the way the brain functions to perceive and act upon the world we live in. You've gained an understanding of neurobiology on a cellular level, and how many diseases and disorders of the nervous system can affect our bodies and minds. In our final module, we will journey into the realms of emotion, attention, memory, and language. By the end of this module, you will have a greater understanding of the more abstract cognitive functions the brain.
What's included
18 videos2 readings1 assignment1 peer review
18 videos•Total 99 minutes
- Introduction to Abstract Function•3 minutes
- Bauby and Emotion•4 minutes
- Thalamic Attention•6 minutes
- Mushroom Hunting•5 minutes
- Memory Types•8 minutes
- PTSD•6 minutes
- Semantic Memories•3 minutes
- Episodic Memories•6 minutes
- The Story of H.M.•5 minutes
- Memory Formation Circuitry•7 minutes
- Hollywood Amnesia•7 minutes
- Clinical Amnesia•6 minutes
- Introduction to Language•4 minutes
- Aphasias•7 minutes
- Prosody•6 minutes
- Intellectual Disability•6 minutes
- Your Brain, Your Illness•6 minutes
- Future Challenges•6 minutes
2 readings•Total 20 minutes
- In-Video Quiz Questions and Answers•10 minutes
- Additional Resources•10 minutes
1 assignment•Total 30 minutes
- Introduction to Abstract Function•30 minutes
1 peer review•Total 120 minutes
- Final Project•120 minutes
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