Lecturio

Biochemistry for Science & Health Careers Specialization

Lecturio

Biochemistry for Science & Health Careers Specialization

Build a Strong Biochemistry Foundation.

Gain the biochemistry foundation behind medicine, dentistry, pharmacy, and engineering careers.

Kevin Ahern, PhD

Instructor: Kevin Ahern, PhD

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Get in-depth knowledge of a subject
Intermediate level

Recommended experience

2 months to complete
at 10 hours a week
Flexible schedule
Learn at your own pace
Get in-depth knowledge of a subject
Intermediate level

Recommended experience

2 months to complete
at 10 hours a week
Flexible schedule
Learn at your own pace

What you'll learn

  • Explain the biochemical pathways governing carbohydrate, lipid, amino acid, and nucleotide metabolism

  • Describe enzyme structure, kinetics, inhibition, and regulation of metabolic pathways

  • Trace DNA replication, transcription, and translation, and how genetic information is repaired

  • Apply biochemistry concepts used across medicine, engineering, and other science careers

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Taught in English
Recently updated!

September 2026

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Specialization - 10 course series

Biochemistry: Foundations

Biochemistry: Foundations

Course 1, 21 hours

What you'll learn

  • Describe the four levels of protein structure and how amino acid sequence determines protein shape

  • Explain how biological membranes and their transport proteins control what enters and exits a cell

  • Trace the central dogma from DNA replication through transcription and translation

  • Discuss core metabolism concepts, including free energy, oxidation-reduction, and pathway regulation

Enzymes and Enzyme Kinetics

Enzymes and Enzyme Kinetics

Course 2, 6 hours

What you'll learn

  • Explain enzyme catalysis, including the induced-fit model and serine protease mechanisms

  • Apply Michaelis-Menten kinetics and interpret Lineweaver-Burk plots

  • Classify enzymes into their six traditional functional classes and describe allosteric regulation

  • Compare competitive, non-competitive, uncompetitive, and irreversible enzyme inhibition

Carbohydrate Metabolism

Carbohydrate Metabolism

Course 3, 9 hours

What you'll learn

  • Describe the reactions and regulation of glycolysis and gluconeogenesis

  • Explain the citric acid cycle, glyoxylate cycle, and ketone body metabolism

  • Describe the pentose phosphate pathway and its role in generating NADPH

  • Explain glycogen synthesis, breakdown, and hormonal regulation

Lipid Metabolism

Lipid Metabolism

Course 4, 5 hours

What you'll learn

  • Explain fat breakdown and synthesis, including beta oxidation of fatty acids

  • Describe the synthesis of glycerophospholipids and sphingolipids in membranes

  • Explain steroid and bile acid metabolism, including the mevalonate pathway

  • Describe receptor-mediated endocytosis of LDL cholesterol

Amino Acid Metabolism

Amino Acid Metabolism

Course 5, 12 hours

What you'll learn

  • Describe the synthesis and breakdown pathways of the major amino acid families

  • Explain nitrogen metabolism and the reactions of the urea cycle

  • Describe heme synthesis and iron homeostasis

  • Explain bilirubin metabolism and its relationship to jaundice

Purine and Pyrimidine Metabolism

Purine and Pyrimidine Metabolism

Course 6, 7 hours

What you'll learn

  • Explain de novo purine and pyrimidine synthesis and their regulation

  • Describe purine and pyrimidine catabolism, salvage, and their role in gout

  • Explain deoxyribonucleotide and thymidine synthesis and the enzymes involved

  • Describe how nucleoside analog drugs interfere with nucleotide metabolism

RNA, DNA and the Genetic Code

RNA, DNA and the Genetic Code

Course 7, 8 hours

What you'll learn

  • Explain DNA replication, including the replication fork and leading/lagging strands

  • Describe the major DNA repair systems and the role of telomeres

  • Explain RNA splicing, catalytic RNAs, and RNA interference

  • Describe the role of chromatin and histones in eukaryotic gene expression

Vitamins

Vitamins

Course 8, 6 hours

What you'll learn

  • Describe the biochemical role of vitamin A in vision and retinoic acid signaling

  • Explain vitamin D's role in calcium homeostasis, including PTH and calcitonin

  • Explain vitamin B12 and folate metabolism

  • Identify the deficiency diseases associated with key vitamins

Hormones and Signal Transduction

Hormones and Signal Transduction

Course 9, 6 hours

What you'll learn

  • Explain G-protein coupled receptor (GPCR) signaling and the role of second messengers

  • Describe receptor tyrosine kinase signaling, including the insulin receptor and EGFR

  • Explain nuclear hormone receptor and steroid hormone signaling

  • Describe how mutations in signaling pathways such as RAS and HER2 contribute to cancer

Metabolic Control

Metabolic Control

Course 10, 6 hours

What you'll learn

  • Explain how insulin and epinephrine regulate fat metabolism through signal transduction

  • Describe reciprocal regulation of glycolysis and gluconeogenesis

  • Explain the Cori cycle and the liver's role in blood glucose regulation

  • Identify how futile cycles are prevented through metabolic regulation

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Instructor

Kevin Ahern, PhD
Lecturio
1 Course6,069 learners

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Lecturio

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