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Bioinformatic Methods I, University of Toronto

4.7
646 ratings
148 reviews

About this Course

Large-scale biology projects such as the sequencing of the human genome and gene expression surveys using RNA-seq, microarrays and other technologies have created a wealth of data for biologists. However, the challenge facing scientists is analyzing and even accessing these data to extract useful information pertaining to the system being studied. This course focuses on employing existing bioinformatic resources – mainly web-based programs and databases – to access the wealth of data to answer questions relevant to the average biologist, and is highly hands-on. Topics covered include multiple sequence alignments, phylogenetics, gene expression data analysis, and protein interaction networks, in two separate parts. The first part, Bioinformatic Methods I (this one), deals with databases, Blast, multiple sequence alignments, phylogenetics, selection analysis and metagenomics. The second part, Bioinformatic Methods II, covers motif searching, protein-protein interactions, structural bioinformatics, gene expression data analysis, and cis-element predictions. This pair of courses is useful to any student considering graduate school in the biological sciences, as well as students considering molecular medicine. Both provide an overview of the many different bioinformatic tools that are out there. These courses are based on one taught at the University of Toronto to upper-level undergraduates who have some understanding of basic molecular biology. If you're not familiar with this, something like https://learn.saylor.org/course/bio101 might be helpful. No programming is required for this course....

Top reviews

By ED

Apr 27, 2017

Great course. All lectures provide a biological context for the tools you learn in the labs. The labs themselves provide a great introduction to the many tools available for bioinformatic analysis.

By FJ

Feb 06, 2017

The videos were very clear on how to use various bioinformatic tools. I found no difficulty in understanding them. Really enjoyed the course. Looking forward to the next part of this course!

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142 Reviews

By Md Shakhawat Hossain

Dec 13, 2018

Just wow! The speciality is the discussion forums

By Miguel Ángel Palacios Pedrero

Nov 30, 2018

Considero este curso de enorme utilidad para aprender de forma eficaz diversos aspectos de la bioinformática. Muy didáctico y bien organizado, por lo que lo recomiendo totalmente.

By Ahmed Hassan

Nov 19, 2018

Very comprehensive and equipped with all basic techniques.

By Fridah G. Wambui Kariuki

Nov 14, 2018

The course was excellent. The labs give a practical feel of what Bioinformatics is. Great work. Looking forward to Part II.

By Roman Petrov

Nov 04, 2018

bioinformatics guide for practical work, great observation of last common use programs and clear explanation of methods

By Mesut Orhan

Oct 27, 2018

Assessments were stressful. I felt that I've learned the some fundamentals of Computational Biology

By 周冰莹

Oct 25, 2018

深入浅出,每个Lab讲解非常详细,很喜欢

By fatima

Oct 06, 2018

it was very useful course . thank you

By Rui Wang

Sep 21, 2018

Highly simplified introduction of bioinformatic methods which is easy to understand even for beginners.

By Arslan Tariq

Aug 16, 2018

Well, the course is well organized, but I think somethings should be included e.g. algorithms of phylogenetic tree methods (UPGMA, Neighborjoing etc).

Thanks a lot.