This course distills for you expert knowledge and skills mastered by professionals in Health Big Data Science and Bioinformatics. You will learn exciting facts about the human body biology and chemistry, genetics, and medicine that will be intertwined with the science of Big Data and skills to harness the avalanche of data openly available at your fingertips and which we are just starting to make sense of. We’ll investigate the different steps required to master Big Data analytics on real datasets, including Next Generation Sequencing data, in a healthcare and biological context, from preparing data for analysis to completing the analysis, interpreting the results, visualizing them, and sharing the results.
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There are 6 modules in this course
After this module, you will be able to 1. Locate and download files for data analysis involving genes and medicine. 2. Open files and preprocess data using R language. 3. Write R scripts to replace missing values, normalize data, discretize data, and sample data.
What's included
11 videos2 readings6 assignments1 discussion prompt
After this module, you will be able to: 1. Locate and download files for data analysis involving genes and medicine. 2. Open files and preprocess data using R language. 3. Write R scripts to replace missing values, normalize data, discretize data, and sample data.
What's included
13 videos4 readings8 assignments1 discussion prompt2 ungraded labs
After this module, you will be able to 1. Select features from highly dimensional datasets. 2. Evaluate the performance of feature selection methods. 3. Write R scripts to select features from datasets involving gene expressions.
What's included
9 videos4 readings6 assignments1 discussion prompt2 ungraded labs
After this module, you will be able to 1. Build classification and prediction models. 2. Evaluate the performance of classification and prediction methods. 3. Write R scripts to classify and predict diseases from gene expressions.
What's included
12 videos4 readings10 assignments1 discussion prompt1 ungraded lab
After this module, you will be able to 1. List different types of gene alterations. 2. Compare and contrast methods for detecting gene mutations. 3. Compare and contrast methods for detecting methylation. 4. Compare and contrast methods for detecting copy number variations. 5. Quantify genomic alterations. 6. Connect genomic alterations to differential expression of genes. 7. Write programs in R for determining gene alterations and their relationship with gene expression.
What's included
9 videos4 readings8 assignments1 discussion prompt1 ungraded lab
After this module, you will be able to 1. Find clusters in biomedical data involving genes.2. Analyze and visualize biological pathways. 3. Write R scripts for clustering and for pathway analysis.
What's included
12 videos5 readings5 assignments1 discussion prompt1 ungraded lab
Instructor
Offered by
Recommended if you're interested in Health Informatics
Korea Advanced Institute of Science and Technology(KAIST)
Duke University
University of California San Diego
Fred Hutchinson Cancer Center
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Frequently asked questions
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