About this Course
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Approx. 18 hours to complete

English

Subtitles: English

Skills you will gain

StatisticsData AnalysisR ProgrammingBiostatistics

100% online

Start instantly and learn at your own schedule.

Flexible deadlines

Reset deadlines in accordance to your schedule.

Approx. 18 hours to complete

English

Subtitles: English

Learners taking this Course are

  • Biologists
  • Biostatisticians
  • Researchers
  • Scientists
  • Data Scientists

Syllabus - What you will learn from this course

Week
1
3 hours to complete

Module 1

21 videos (Total 129 min), 3 readings, 1 quiz
21 videos
What is Statistics?2m
Finding Statistics You Can Trust (4:44)4m
Getting Help (3:44)3m
What is Data? (4:28)4m
Representing Data (5:23)5m
Module 1 Overview (1:07)1m
Reproducible Research (3:42)3m
Achieving Reproducible Research (5:02)5m
R Markdown (6:26)6m
The Three Tables in Genomics (2:10)2m
The Three Tables in Genomics (in R) (3:46)3m
Experimental Design: Variability, Replication, and Power (14:17)14m
Experimental Design: Confounding and Randomization (9:26)9m
Exploratory Analysis (9:21)9m
Exploratory Analysis in R Part I (7:22)7m
Exploratory Analysis in R Part II (10:07)10m
Exploratory Analysis in R Part III (7:26)7m
Data Transforms (7:31)7m
Clustering (8:43)8m
Clustering in R (9:09)9m
3 readings
Syllabus10m
Pre Course Survey10m
Introduction and Materials10m
1 practice exercise
Module 1 Quiz20m
Week
2
2 hours to complete

Module 2

14 videos (Total 97 min), 1 quiz
14 videos
Dimension Reduction (12:13)12m
Dimension Reduction (in R) (8:48)8m
Pre-processing and Normalization (11:26)11m
Quantile Normalization (in R) (4:49)4m
The Linear Model (6:50)6m
Linear Models with Categorical Covariates (4:08)4m
Adjusting for Covariates (4:16)4m
Linear Regression in R (13:03)13m
Many Regressions at Once (3:50)3m
Many Regressions in R (7:21)7m
Batch Effects and Confounders (7:11)7m
Batch Effects in R: Part A (8:18)8m
Batch Effects in R: Part B (3:50)3m
1 practice exercise
Module 2 Quiz20m
Week
3
2 hours to complete

Module 3

15 videos (Total 86 min), 1 quiz
15 videos
Logistic Regression (7:03)7m
Regression for Counts (5:02)5m
GLMs in R (9:28)9m
Inference (4:18)4m
Null and Alternative Hypotheses (4:45)4m
Calculating Statistics (5:11)5m
Comparing Models (7:08)7m
Calculating Statistics in R9m
Permutation (3:26)3m
Permutation in R (3:33)3m
P-values (6:04)6m
Multiple Testing (8:25)8m
P-values and Multiple Testing in R: Part A (5:58)5m
P-values and Multiple Testing in R: Part B (4:23)4m
1 practice exercise
Module 3 Quiz20m
Week
4
2 hours to complete

Module 4

14 videos (Total 74 min), 1 reading, 1 quiz
14 videos
Gene Set Enrichment (4:19)4m
More Enrichment (3:59)3m
Gene Set Analysis in R (7:43)7m
The Process for RNA-seq (3:59)3m
The Process for Chip-Seq (5:25)5m
The Process for DNA Methylation (5:03)5m
The Process for GWAS/WGS (6:12)6m
Combining Data Types (eQTL) (6:04)6m
eQTL in R (10:36)10m
Researcher Degrees of Freedom (5:49)5m
Inference vs. Prediction (8:52)8m
Knowing When to Get Help (2:31)2m
Statistics for Genomic Data Science Wrap-Up (1:53)1m
1 reading
Post Course Survey10m
1 practice exercise
Module 4 Quiz10m
4.1
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Top reviews from Statistics for Genomic Data Science

By ZMJun 28th 2018

The professor is really enthusiasm, so I was really impreesed by him. And his teaching is brief, and I can learn key points through the lectures. Great course!

By LRMay 23rd 2016

I have really enjoyed the course and I have learnt different concepts relevant for my current study.\n\nYurany

Instructor

Avatar

Jeff Leek, PhD

Associate Professor, Biostatistics
Bloomberg School of Public Health

About Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

About the Genomic Data Science Specialization

With genomics sparks a revolution in medical discoveries, it becomes imperative to be able to better understand the genome, and be able to leverage the data and information from genomic datasets. Genomic Data Science is the field that applies statistics and data science to the genome. This Specialization covers the concepts and tools to understand, analyze, and interpret data from next generation sequencing experiments. It teaches the most common tools used in genomic data science including how to use the command line, along with a variety of software implementation tools like Python, R, Bioconductor, and Galaxy. This Specialization is designed to serve as both a standalone introduction to genomic data science or as a perfect compliment to a primary degree or postdoc in biology, molecular biology, or genetics, for scientists in these fields seeking to gain familiarity in data science and statistical tools to better interact with the data in their everyday work. To audit Genomic Data Science courses for free, visit https://www.coursera.org/jhu, click the course, click Enroll, and select Audit. Please note that you will not receive a Certificate of Completion if you choose to Audit....
Genomic Data Science

Frequently Asked Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

More questions? Visit the Learner Help Center.